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硝唑尼特的来源
从HCV medhelp 转来的。加上HBV medhelp里面stefano170669战友的帖子和查找的信息，这个药治疗HBV的希望应该是相当大的。有可能是又一个阿德福韦和替诺福韦的故事。
建议抗病毒药都耐药的战友可以考虑一试，价格便宜，也不用考虑耐药和停药的问题。
Alinia (Nitazoxanide) Sources
by mike716, Dec 13, 2009 10:40PM
Hi, fellow medhelpers! At the risk of becoming a pest and annoying those who don't love me (yes, such people do seem to exist and they're not all doctors, I fearFears and phobias), I'm posting again. However, this is not a "give me" post, but a "giving back" post.
I spent some time recently searching for info on and sources of AliniaAlinia (one brand name), or nitazoxanide (the chemical name). I thought I'd share some of the information with you.
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First-testosterone mc, names. Nitazoxanide comes in so many different brand names that I can only list a few. AliniaAlinia was the first, and is the drug name given to nitazoxanide by its discoverer, Dr. Jean-Francois Rossignol, who works at the Pasteur Institute in Paris. The Pasteur Institute is where the AIDS virus was first isolated and identified (despite claims to the contrary by certain less-than-forthright persons at the National Institute of Health in Washington). Dr. Rossignol is part of a company called Romark Laboratories, in Tampa, Florida, which manufactures Alinia and is running the current trials for its use as an adjunct therapy with SOC.
Romark has licensed certain other manufacturers to produce nitazoxanide. These are the less-expensive equivalents that can be found, for example, in Europe and Canada and a few other places that still respect patents and copyrights. In places that don't, nitazoxanide is produced by a plethora of small-ish pharmaceutical companies under a myriad of brand names. A few of them are: Daxon, Dexidex, Pacovanton, Paramix, Nitax, Zox, Nitazox, Toza, Zóntricon, Celectan, Nixoran, Dexidex, Kidonax, Nitanid, Colufase, Nodik, Paraxin, Rosanil, Nitaxom, Noxolin, Uniplus7, Nitaxin, Nitapax, Zoxanid, Nitarid, Bionit, Rosanil, Parsenida, Zotanixin.
Who thinks up all these silly names? It makes you wonder...
Anyway, these are all nitazoxanide, or pretend to be. The ones that are manufactured in places where there isn't much control over pharmaceuticals might not be exactly the same formula as the nitazoxanide used in Alinia. On the other hand, it isn't a very complex chemical so there's really not much point in them using anything else (unless it's sugar or talc).
One point about the chemical contents that could be important, though, is that Romark appears to be using a time-release formulation of nitazoxanide in the Alinia used in their trials. I sincerely doubt that any of these other nitazoxanides are time-release.
Prices vary widely, as one would imagine. And since the Internet has spawned huge industries of online wholesalers, retailers, and geographically-unidentifiable resellers of everything under the sun including pharmaceuticals, there are places (I use this term in its broadest virtual sense) where you can buy nitazoxanide, or something that looks very much like it, for a small fraction of what the name brand companies sell it for. Here's a list of the ones I've had time to look at, together with price data:
===========================================
http://www.wisemeds.net/buy_online/Nitarid.shtml
***@****
Nitarid
Glenmark Ltd.
500mg x 60 Tablets $55.42 ($0.92/tablet)
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http://www.brandprescriptiondrugs.com/Nitazoxanide.htm (Int'l comparison site)
Nitarid
Cipla Ltd. (India)
2 x 60 tabs x 500mg $ 99.65 ($0.83/tablet)
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http://www.generics.ws/shopping_carts/show/
(India)
Nizonide
Lupin Pharm.
12 x 2 = 24 for $18.96 = ($0.79/tablet)
===========================================
OnlinePharmaciesCanada.com
(Canada)
Generic 500mg 60 Tablets $73.79 ($1.23/tablet)
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http://www.farmasana.com.mx/productos.pdf
(Mexico)
Kidonax
65 pesos = 5USD /bottle of 6 x 500mg ($0.83/tablet)
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Nitaxin - Qualifarm SA in Guatemala
(Guatemala)
6 tablets x 500mg 69 Quetzals = 8 USD ($1.33/tablet)
Teléfono: 2414 4242
Fax: 23371560
4ta. Avenida 19-33, zona 14
Guatemala, Guatemala
===========================================
http://patientindia.com/resultDe ... 7&brandId=10880
(India)
NIZONIDE 6 x ? 45.36 Lupin Laboratories
===========================================
http://chemistparadise.com/Nizonide_500_mg-d-32183.html
(India)
Nizonide 500 mg
Name: Nizonide
Manufacturer: Lupin Laboratories Ltd. (Pinnacle)
Form: Tablet
Dosage: 500 mg
Packing: 10
Chemical name: Nitazoxanide
Price: 3.50 ($1.67/tablet)
Others:
Brand: Manufacturer: Dosage: Price:
Zimdax DT US Vitamins Limited 200 mg 2.50
Mehulox Heal All Pharmaceuticals (P) Ltd. 500mg 3.50
Mehulox DT Heal All Pharmaceuticals (P) Ltd. 200mg 2.50
Nitacure Alembic Chemical Works Co Ltd 200mg 3.67
Nitarid Cipla Limited 500mg 6.25
Nitarid DT Cipla Limited 200mg 4.42
Nitcol Rexcel Pharmaceuticals 500mg 5.83
Nitcol DT Rexcel Pharmaceuticals 200mg 4.17
Zstop Svizera Healthcare (Sigma Division) 200mg 4.42
Nizonide Lupin Laboratories Ltd. (Pinnacle) 500 mg 3.50
Nizonide DT Lupin Laboratories Ltd. (Pinnacle) 200 mg 7.50
Zimdax DT (500 mg) US Vitamins Limited 500 mg 3.50
Zoxakind Mankind Pharmaceuticals Pvt. Ltd. 500 mg 5.0
Chemical4u Ltd.
26 Parkridge Road
Ward Hill, Mumbai 01835 India
Catalog sales: +91-800-343-0660 or 978-521-6300
Bulk/Specialty Sales: +91-888-343-8025
***@****
FAX: +91 101 889 9898
===========================================
http://www.mexmeds4you.com/productdetails.asp?pid=1886
(Mexico)
Nitazoxinide Generic - 500 mg
Package Size: 6 tabs
Price: $10 ($1.67/tablet)
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http://www.progressiverx.com/sto ... e=search&page=1
(Canada)
Alinia (Nitazoxanide)
60 Pills x 500 mg $71.99 ($1.20/tablet)
===========================================
Whew! There sure is a lot of nitazoxanide around. And it seems to be getting cheaper by the minute.
Now, some of these companies (I use the term loosely) may require a prescription, or say they do. Others don't. Still others make believe they do but give you unusual ways of showing you've got one, like emailing a scan of a prescribed bottle label! People need to investigate these details and deal with them individually (like most other things in this sad, strange world).
I hope this info is of some use. I personally believe that nitazoxanide has been shown to work and that it beats doing SOC alone, especially for us gt1 infectees. Being gt1, 65 years old, and having a high viral load and low platelets, I figure my chances of SVRing with SOC are around 20%. So I'm not going to Tx with just SOC, I'll add nitazoxanide. It makes sense.
Cheers!
Mike |
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楼主: 闹心啊
发表于 2010-2-13 14:58
