本帖最后由 StephenW 于 2011-3-25 20:42 编辑
渠水欢歌 发表于 2011-3-25 20:29
1.14.“乙型肝炎不是乙肝病毒直接伤害而是免疫间接伤害”的经典理论,不能解释为何DNA阴性而表面抗原阳性者 ...
http://www.hbvhbv.com/forum/thread-1019857-2-1.html 他说不能解释三点,我提出我的解释.他没有回答.
StephenW:
"不能解释为何肝脏炎性细胞集中于汇管区而不是集中在血运更加丰富的肝窦" - 为什么不能解释? 在肝窦的墙壁铺有吞噬细胞,称为枯否细胞,消化旧的红血细胞和血液中的毒素清除。 肝细胞分离,由狄氏空间的血窦。 Kupffer细胞是位于内血窦和可以占用和破坏外来物质如细菌。 http://en.wikipedia.org/wiki/Liver_sinusoid
A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serves as a location for the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.[1]
Hepatocytes are separated from the sinusoids by the space of Disse. Kupffer cells are located inside the sinusoids and can take up and destroy foreign material such as bacteria.
Basic liver structure
Human liver sinusoid
阿肝血窦是一种正弦血管型(有孔,不连续的内皮细胞),它作为为富含氧气的血液由肝动脉和门静脉从营养丰富的血液供应的位置[1]。
肝细胞分离,由狄氏空间的血窦。 Kupffer细胞是位于内血窦和可以占用和破坏外来物质如细菌。
sinusoid, irregular tubularspace for the passage of blood, taking the place of capillaries and venules inthe liver, spleen, and bone marrow. The sinusoids form from branches of the portal vein in the liver and fromarterioles (minute arteries) in other organs. The walls of the sinusoids arelined with phagocytic cells, called Kupffer cells, that digest old red blood cells and clear the bloodstream oftoxins.
In the liver, blood enters the hepatic sinusoids from both the portal vein and the hepatic artery; the venous blood iscleansed in the sinusoids, while the arterial blood provides oxygen to the surrounding liver cells. Blood then passes from the sinusoids into the hepatic vein for return to the heart.
肝血窦,不规则管状空间的血液通过参与肝,脾的毛细血管和小静脉的地方,和骨髓。从形式的血窦在肝脏和其他器官中动脉(分钟动脉)门静脉分支。在正肝血窦的墙壁铺有吞噬细胞,称为枯否细胞,消化旧的红血细胞和血液中的毒素清除。
在肝脏,同时从血液进入门静脉,肝动脉,肝血窦;静脉血液净化的正肝血窦,而动脉血提供氧气给周围的肝细胞。然后通过对血液回流到心脏,肝静脉进入的血窦。 |