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china5star 发表于 2022-12-29 16:08
高人是讲过了 后悔当初没有信 没有仔细看
再贴出来 让大家认清hifive这个骗子的真面目
研究了一下,这个论文说,替诺吃5年才能部分人逆转肝硬化,是5年,不是1年!
而且恩替效果差于替诺,所以恩替要逆转纤维化要更长的时间!
2016年我看stanford的Garcia大夫时,他当时跟我说Cirrhosis无法逆转,所以推测当时西医界对替诺的效果还认知不足。
https://pubmed.ncbi.nlm.nih.gov/23234725/
Findings: Of 641 patients who received randomised treatment, 585 (91%) entered the open-label phase, and 489 (76%) completed 240 weeks. 348 patients (54%) had biopsy results at both baseline and week 240. 304 (87%) of the 348 had histological improvement, and 176 (51%) had regression of fibrosis at week 240 (p<0·0001). Of the 96 (28%) patients with cirrhosis (Ishak score 5 or 6) at baseline, 71 (74%) no longer had cirrhosis (≥1 unit decrease in score), whereas three of 252 patients without cirrhosis at baseline progressed to cirrhosis at year 5 (p<0·0001). Virological breakthrough occurred infrequently and was not due to resistance to tenofovir DF. The safety profile was favourable: 91 (16%) patients had adverse events but only nine patients had serious events related to the study drug.
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