慢性乙型肝炎患者抑郁症状的社会经济脆弱性

StephenW

Int J Environ Res Public Health. 2019 Jan 17;16(2). pii: E255. doi: 10.3390/ijerph16020255.
Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B.
Vu TTM1, Le TV2, Dang AK3, Nguyen LH4, Nguyen BC5, Tran BX6,7, Latkin CA8, Ho CSH9, Ho RCM10,11.
Author information

1
    Hanoi Medical University, Hanoi 100000, Vietnam. [email protected].
2
    Viet-Tiep Friendship Hospital, Hai Phong 180000, Vietnam. [email protected].
3
    Institute for Global Health Innovations, Duy Tan University, Da Nang 550000, Vietnam. [email protected].
4
    Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam. [email protected].
5
    Viet-Tiep Friendship Hospital, Hai Phong 180000, Vietnam. [email protected].
6
    Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, Vietnam. [email protected].
7
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA. [email protected].
8
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA. [email protected].
9
    Department of Psychological Medicine, National University Hospital, Singapore 119074, Singapore. [email protected].
10
    Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam. [email protected].
11
    Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore. [email protected].

Abstract

Depression is considered one of the most prevalent psychiatric disorders among patients with hepatitis B virus (HBV)-related liver disease and has adverse effects on the disease progression. However, there is a scarcity of studies contributing to the assessement of depression in hepatitis B patients. There is also little research into risk factors, particularly underlying socio-economic factors in Vietnam where the prevalence of hepatitis B is high. This study aimed to examine depression and identify whether differences in socio-economic status is related to the level of depression amongst chronic hepatitis B patients. A cross-sectional study was conducted on 298 patients with chronic hepatitis B at The Chronic Hepatitis Clinic in the Viet-Tiep Hospital, Hai Phong, Vietnam. The Patient Health Questionnaire-9 (PHQ-9) and EuroQol-5 dimensions-5 levels (EQ-5D-5L) were used to assess the severity of depression and health-related quality of life (HRQOL). Of chronic hepatitis B patients, 37.5% experienced depressive symptoms and most of them suffered minimal depressive symptoms (31.4%). According to the result of the multivariate logistic regression model, we found that higher age, lower income level, unemployement, living with spouse/partners were positively associated with having depression. Furthermore, having physical health problems and lower health-related quality of life were also related to a higher risk of depression. We recommend family support, financial support and active participation in consultation should be conducted during treatment to improve the quality of life and the emotional state of HBV patients.
KEYWORDS:

Vietnam; chronic hepatitis B; depressive symptoms; inequality; socioeconomic

PMID:
    30658423
DOI:
    10.3390/ijerph16020255

StephenW

Int J Environ Res Public Health。 2019年1月17日; 16（2）。 pii：E255。 doi：10.3390 / ijerph16020255。
慢性乙型肝炎患者抑郁症状的社会经济脆弱性
Vu TTM1，Le TV2，Dang AK3，Nguyen LH4，Nguyen BC5，Tran BX6,7，Latkin CA8，Ho CSH9，Ho RCM10,11。
作者信息

1
    河内医科大学，越南河内100000。 [email protected]。
2
    Viet-Tiep友谊医院，海防180000，越南。 [email protected]。
3
    杜伊坦大学全球健康创新研究所，越南岘港550000。 [email protected]。
4
    越南胡志明市Nguyen Tat Thanh大学行为医学卓越中心700000。 [email protected]。
五
    Viet-Tiep友谊医院，海防180000，越南。 [email protected]。
6
    河内医科大学预防医学与公共卫生研究所，越南河内100000。 [email protected]。
7
    彭博社公共卫生学院，约翰霍普金斯大学，巴尔的摩，MD 21205，USA。 [email protected]。
8
    彭博社公共卫生学院，约翰霍普金斯大学，巴尔的摩，MD 21205，USA。 [email protected]。
9
    新加坡国立大学医院心理医学系，新加坡119074。 [email protected]。
10
    越南胡志明市Nguyen Tat Thanh大学行为医学卓越中心700000。 [email protected]。
11
    新加坡国立大学Yong Loo Lin医学院心理医学系，新加坡119228，新加坡。 [email protected]。

抽象

抑郁被认为是乙型肝炎病毒（HBV）相关肝病患者中最常见的精神疾病之一，并且对疾病进展有不良影响。然而，缺乏有助于评估乙型肝炎患者抑郁症的研究。对于危险因素的研究也很少，尤其是越南乙型肝炎患病率高的潜在社会经济因素。本研究旨在研究抑郁症，并确定社会经济状况的差异是否与慢性乙型肝炎患者的抑郁水平有关。在越南海防的Viet-Tiep医院的慢性肝炎诊所对298名慢性乙型肝炎患者进行了横断面研究。患者健康问卷-9（PHQ-9）和EuroQol-5维度-5水平（EQ-5D-5L）用于评估抑郁症和健康相关生活质量（HRQOL）的严重程度。在慢性乙型肝炎患者中，37.5％的患者出现抑郁症状，其中大多数患者的抑郁症状很轻微（31.4％）。根据多变量逻辑回归模型的结果，我们发现年龄越大，收入水平越低，失业，与配偶/伴侣共同生活与抑郁呈正相关。此外，身体健康问题和与健康相关的生活质量下降也与抑郁症的高风险有关。我们建议在治疗期间进行家庭支持，经济支持和积极参与咨询，以改善HBV患者的生活质量和情绪状态。
关键词：

越南;慢性乙型肝炎;抑郁症状;不等式;社会经济

结论：
    30658423
DOI：
    10.3390 / ijerph16020255

StephenW

https://www.mdpi.com/1660-4601/16/2/255