Int J Environ Res Public Health. 2019 Jan 17;16(2). pii: E255. doi: 10.3390/ijerph16020255.
Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B.
Vu TTM1, Le TV2, Dang AK3, Nguyen LH4, Nguyen BC5, Tran BX6,7, Latkin CA8, Ho CSH9, Ho RCM10,11.
Author information
1
Hanoi Medical University, Hanoi 100000, Vietnam. [email protected].
2
Viet-Tiep Friendship Hospital, Hai Phong 180000, Vietnam. [email protected].
3
Institute for Global Health Innovations, Duy Tan University, Da Nang 550000, Vietnam. [email protected].
4
Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam. [email protected].
5
Viet-Tiep Friendship Hospital, Hai Phong 180000, Vietnam. [email protected].
6
Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, Vietnam. [email protected].
7
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA. [email protected].
8
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA. [email protected].
9
Department of Psychological Medicine, National University Hospital, Singapore 119074, Singapore. [email protected].
10
Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam. [email protected].
11
Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore. [email protected].
Abstract
Depression is considered one of the most prevalent psychiatric disorders among patients with hepatitis B virus (HBV)-related liver disease and has adverse effects on the disease progression. However, there is a scarcity of studies contributing to the assessement of depression in hepatitis B patients. There is also little research into risk factors, particularly underlying socio-economic factors in Vietnam where the prevalence of hepatitis B is high. This study aimed to examine depression and identify whether differences in socio-economic status is related to the level of depression amongst chronic hepatitis B patients. A cross-sectional study was conducted on 298 patients with chronic hepatitis B at The Chronic Hepatitis Clinic in the Viet-Tiep Hospital, Hai Phong, Vietnam. The Patient Health Questionnaire-9 (PHQ-9) and EuroQol-5 dimensions-5 levels (EQ-5D-5L) were used to assess the severity of depression and health-related quality of life (HRQOL). Of chronic hepatitis B patients, 37.5% experienced depressive symptoms and most of them suffered minimal depressive symptoms (31.4%). According to the result of the multivariate logistic regression model, we found that higher age, lower income level, unemployement, living with spouse/partners were positively associated with having depression. Furthermore, having physical health problems and lower health-related quality of life were also related to a higher risk of depression. We recommend family support, financial support and active participation in consultation should be conducted during treatment to improve the quality of life and the emotional state of HBV patients.
KEYWORDS:
Int J Environ Res Public Health。 2019年1月17日; 16（2）。 pii：E255。 doi：10.3390 / ijerph16020255。
慢性乙型肝炎患者抑郁症状的社会经济脆弱性
Vu TTM1，Le TV2，Dang AK3，Nguyen LH4，Nguyen BC5，Tran BX6,7，Latkin CA8，Ho CSH9，Ho RCM10,11。
作者信息