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本帖最后由 StephenW 于 2012-5-20 16:35 编辑
VIRAL BIOMARKERS IN THE BLOOD COMPARTMENT: RESEARCH AND DIAGNOSTIC
TOOLS
Specific serology has proven to be the mainstay of diagnostic testing for hepatitis B. Several commercial immunoassays are available for the various hepatitis B markers of viral antigens and antibodies. [52] Recently, sensitive and reliable assays have been developed to quantify serum HBsAg and HBeAg. Quantitative HBsAg levels are reported in
IU/ml, with 0.1 IU/ml being equivalent to approximately 0.1 ng/ml of HBsAg,[53] which is in turn equivalent to 2x10**7 subviral HBsAg particles or 5x10**6 virions. For HBeAg measurement, most quantitative assays are modified by reference to an external standard, such as the Paul Ehrlich (PE) Institute reference standard for HBeAg, and results are expressed in PE IU/ml.[54]
血液中的病毒标志物的
研究和诊断 工具
特定的血清已被证明是支柱B型肝炎的几个商业的诊断测试免疫是可用的各种乙肝标志物的病毒抗原和抗体。[52]近日,灵敏,可靠的检测 已发展到定量血清HBsAg和HBeAg。定量HBsAg水平报告国际单位/毫升,0.1 IU/毫升,相当于大约0.1毫微克/毫升的HBsAg,[53]这进而相当于2x10**7病毒表面抗原颗粒或5x10**6病毒颗粒。对于HBeAg测量,最定量分析,通过引用被修改外部标准,如保罗·埃利希(PE)研究所的参考标准,对于HBeAg 结果
是PE IU/ml [54]表示.
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