Your Address, Ethnicity and Drug Use Determine Your HBV Genotype

liver411

Your Address, Ethnicity and Drug Use Determine Your HBV Genotype

The U.S. Centers for Disease Control and Prevention analyzed blood samples from 614 patients who experienced acute, or new, hepatitis B infections in six counties nationwide that participate in the Sentinel Counties Study of Acute Viral Hepatitis between 1999 and 2005.

Researchers wanted to know which hepatitis B strains or genotypes were spreading most rapidly in this sample population.

There are eight genotypes (A-H), and each genotype evolved in specific geographic areas of the world. For example, genotype A is prevalent in northwestern Europe, North America, and Africa; genotypes B and C are common in Asia; genotype D is most frequently found in the Mediterranean area; genotype E is prevalent in Africa; genotype F is prevalent in the aboriginal populations of South America; genotype G is found in Europe and the U.S., and genotype H is prevalent in the Amerindian populations of Central America.

As expected, all HBV genotypes are found in the United States, with genotype A commonly found in white and African-American patients and genotypes B and C found in Asian-Americans.

According to the report on new HBV infections, published in the August 2011 issue of the journal of Clinical Infectious Diseases:

75% of new HBV infections were genotype A
18% were infected with genotype D
Genotype A infections (compared with genotype D) were five times greater among African-Americans than among Hispanics.

The odds of infection with genotype A were 49-, 8-, and 4-times higher in patients from Jefferson County (Alabama), Pinellas County (Florida), and San Francisco (California), respectively, than among those living in Denver County (Colorado).

Genotype A was less common among recent injection drug users than it was among non-injection drug users.

Researchers concluded that ethnicity, geographic residence, and injecting drug use greatly determined a hepatitis B patient’s genotype.

HBV J



(6.合.彩)足球.篮球...各类投注开户下注

第一投注现金网:招代理年薪10万以上:yyu.cc