[英语研究]中国东南 B型肝炎盛行率

StephenW

Eur J Gastroenterol Hepatol. 2011 May 26. [Epub ahead of print]

Prevalence of hepatitis B in the southeast of China: a population-based
study with a large sample size.

Luo Z, Xie Y, Deng M, Zhou X, Ruan B.

Source
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,
The First Affiliated Hospital, College of Medicine, Zhejiang University,
Hangzhou, People's Republic of China.

Abstract

OBJECTIVE:
Hepatitis B is a major public health problem in China. However, in the past
10 years, estimates of the prevalence of hepatitis B virus (HBV) have been
sparse, with results that do not always agree. The purpose of this study
was to investigate the epidemiology of HBV in adults and to provide the
most recent baseline data for planning and monitoring of health.

METHODS:
The prevalence of HBV was determined in a community-based, cross-sectional,
age-stratified sample of adults (aged 20 years or older). The study
population was selected using random multistage cluster sampling.
Demographic information and serological samples were obtained from 19 933
participants.

RESULTS:
The prevalence of anti-HBV core antibody, HBV surface antigen (HBsAg), and
anti-HBV surface antibody was 38.6, 7.9, and 44.9%, respectively. We found
statistically significant differences in hepatitis B infection between men
and women (P<0.001). The prevalence of HBV infection increased with age.
The rates of HBsAg positivity and HBV infection in individuals living on an
island were higher than those of individuals living in plains. The alanine
aminotransferase level was elevated (กร38 IU/l) in 15.7 and 7.2% of
HBsAg-positive and HBsAg-negative patients; the proportion of elevated
alanine aminotransferase was markedly higher in men (12.7%) than in women
(4.7%) (P<0.001). The ฅแ-fetoprotein-positive rate was 2% in HBsAg-positive
individuals who were aged 30 years or older.

CONCLUSION:
Borderline intermediate/high endemicity was found among adults in the
northern region of Zhejiang Province. The vaccination program has
contributed to a reduction in infection over the last 20 years, although
further efforts are required to turn the region into a 'low-endemicity'
area.



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StephenW

肝炎在中国东南乙患病率：以人口为基础的
研究大样本的大小。

罗Z的谢英，邓男，周新民，阮二

来源
国家对诊断和治疗传染病重点实验室，
第一附属医院，医学院，浙江大学，
杭州，人们对中国共和国。

摘要

目的：
乙型肝炎是中国一个主要的公共卫生问题。然而，在过去
10年来，B型肝炎病毒（HBV）的患病率估计已
稀疏，其结果并不总是同意。本研究的目的
在探讨成人乙型肝炎病毒流行病学及提供
规划和健康监测的最新基准数据。

方法：
HBV的流行是确定的，以社区为基础，截面，
年龄分层抽样的成年人（20岁或以上）。该研究
采用随机选择了人口多级整群抽样。
人口信息和血清样本取自19 933
参与者。

结果：
反乙肝病毒核心抗体盛行率，乙肝病毒表面抗原（HBsAg），以及
抗乙肝病毒表面抗体为38.6，7.9，和44.9％，分别为。我们发现
统计学显着性差异男女之间乙肝病毒感染
和妇女（P“0.001）。对乙肝病毒感染率随年龄增加而增加。
在个人的HBsAg阳性和HBV感染对一个生活率
岛上的生活比在平原个人高。丙氨酸
转氨酶水平升高（กร38国际单位/升）的15.7和7.2％
乙肝表面抗原阳性和乙肝表面抗原阴性的患者，这个比例升高
谷丙转氨酶显着，男性（12.7％）高于女性
（4.7％），性（P“0.001）。该ฅแ甲胎蛋白阳性率分别为2乙肝表面抗原阳性％
谁是30岁或以上的个人。

结论：
边缘中级/高流行被发现在成年人
浙江省北部地区。疫苗接种计划
促成了感染，在过去20年减少，虽然
需要进一步努力变成一个'低流行，该地区
区。

结论：21617533 [PubMed的 - 由出版商提供]