Overweight teenagers run risk of liver disease

StephenW

http://www.smh.com.au/lifestyle/wellbeing/overweight-teenagers-run-risk-of-liver-disease-20110325-1c9u8.html
                    Overweight teenagers run risk of liver disease                                                                                    Amy Corderoy                March 26, 2011   



                                AUSTRALIAN teenagers are becoming so overweight they are doing the type of damage to their livers that would normally be seen in older alcoholics, researchers have found.
            The researchers discovered a condition called fatty liver disease, which is normally found in older people who are overweight or obese, heavy drinkers, or have chronic conditions such as hepatitis, in about 13 per cent of the 17-year-olds they tested.
            The study of 1170 otherwise healthy West Australian teenagers also found a further 3 per cent who had the condition but were drinking large enough quantities of alcohol that it could not be ruled out as the source of the problem.
               
            This is the first generation of teenagers to have high enough rates of overweight and obesity that doctors needed to look for the condition, said the study leader, Dr Oyekoya Ayonrinde. But the lack of information from other generations meant the long-term complications for teenagers with the disease remained unknown.
            Fatty liver disease, which occurs when fat builds up to become more than 10 per cent of the liver's weight, can lead to inflammation and scarring.   In serious cases, when cirrhosis of the liver occurs, it can lead to liver failure and even death.
            The teenagers with basic fatty liver disease would often have no symptoms besides excess weight. Yet they were at risk of metabolic conditions such as Type 2 Diabetes and heart disease,  said Dr Ayonrinde, a gastroenterologist and hepatologist from Freemantle Hospital and the University of Western Australia.
            "The disease is common and it is underdiagnosed … that potentially results in missed opportunities to identify and address metabolic risk factors in people who have it," he said.
            His study, published in the journal Hepatology, found the condition was more common in girls, but that boys tended to have a more severe form of it.
            Jacob George, a professor of hepatic medicine at the University of Sydney, said 20 years ago doctors never saw children with cirrhosis or liver failure, but now were reporting seeing such cases. "One of the other issues is that traditionally people got fatty liver disease as adults and by the time they were getting to liver disease and liver failure they were in their 60s and 70s," he said.
            This meant if the lifestyles of the teenagers with the condition did not improve they could experience serious liver problems in their 30s and 40s.
            Professor George said it was likely that obesity could take over from hepatitis and alcoholism as the biggest single cause of liver failure and liver cancer.
            "The number of people with the disease is so huge that if even a fraction get liver cancer it is going to be huge," he said.
            The chief executive of Cancer Council Australia, Ian Olver, said increasing rates of child and teenage obesity would also lead to a rise in other, more common cancers such as bowel and breast cancer.
            "Traditionally people have associated obesity more with heart disease and diabetes and they are both problems but it has been newer information that obesity is associated with cancers," he said. "But it is a preventable risk factor, when others such as your genes you can't prevent."
   



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StephenW

超重青少年肝脏疾病的危险
艾米Corderoy为
2011年3月26日



澳洲青少年变得如此超重，他们在做什么类型的损坏他们通常会出现在老年人酗酒肝，研究人员发现。

研究人员发现了一种情况称为脂肪肝疾病，通常是在老年人中，谁是超重或肥胖，酗酒者，或有慢性肝炎等条件的大约13，占17岁的年轻人，他们发现百分之测试。

1170原本健康的西澳洲青少年研究还发现，百分之谁的条件，但喝的酒足够大，它也不能排除作为问题的根源出数量进一步3。


这是对青少年进行第一代有足够高的超重和肥胖率，需要寻求医生的条件，说，这项研究的领导者，医生Oyekoya Ayonrinde。但是，从信息的缺乏意味着其他世代与疾病的青少年的长期并发症不明。

脂肪肝疾病，即当脂肪积聚，成为超过了肝脏重量的百分之十，可导致炎症和疤痕。在严重的情况下，当肝硬化的发生，它可导致肝功能衰竭，甚至死亡。

脂肪肝的基本病的青少年往往有除了多余的体重没有任何症状。然而，他们在诸如2型糖尿病和心脏病的代谢状况的危险，医生说Ayonrinde，肠胃和弗里曼特尔医院和西澳大利亚大学肝病。

“疾病是常见​​的，它是未被诊断，在错失机会...可能结果来确定和解决人谁也代谢危险因素，”他说。

他的研究，在期刊杂志发表时，发现在女孩条件更常见，但那个男生往往有一个更为严重。

雅各布乔治，一个肝药在悉尼大学教授，医生说，20年前从未见过肝硬化或肝功能衰竭的孩子，但是现在看到这种情况被报告。 “另外一个问题是，传统的人化装成脂肪肝疾病，成年人的时候，他们要对肝脏疾病和肝功能衰竭他们在60年代和70年代了，”他说。

这意味着如果与青少年的生活条件得不到改善，他们能体验到在30多岁和40岁严重的肝脏问题。

乔治教授说，肥胖可能会从肝炎和酗酒对作为最大的肝衰竭和肝癌的唯一原因。

“人与疾病的人数是如此巨大，即使只有一小部分得到肝癌这将是巨大的，”他说。

澳大利亚的癌症理事会，伊恩奥尔弗，行政长官说，儿童和青少年肥胖率持续上升也将导致其他更普遍，如肠癌和乳腺癌癌症将会上升。

“传统上更多的人有相关的肥胖与心脏病和糖尿病，他们这两个问题，但已较新的资料，肥胖与癌症有关，”他说。 “但它是一种可以预防的危险因素，如当别人你的基因，你无法阻止。”