Viral vaccine composition, process and methods of use, the patent of IMMUNITOR

batibaby

original link：http://www.freepatentsonline.com/7838006.htmlAbstract：
A composition for treating or preventing virus-induced infections is described, along with a process of producing the composition and methods of the composition's use. The composition comprises viral pathogen-infected cell or tissue, or malignantly or immunologically aberrant cells or tissues which has been reduced and/or denatured. The preferred composition is administered across a mucosal surface of an animal suffering or about suffer from infection. The composition is administered as preventive or therapeutic vaccine.



Claims:
What is claimed is:

1. A composition comprising denatured hepatitis type B or type C viral pathogen, wherein the pathogens are denatured through a method comprising drying the pathogen and denaturing the resulting dried pathogen using heat alone, wherein the composition is formulated as an oral pill.

2. The composition process of claim 1, wherein the hepatitis viral pathogen is hepatitis B virus.

3. The composition of claim 1, wherein the hepatitis viral pathogen is hepatitis C virus.

4. The composition of claim 1, wherein said composition is formulated without an immune adjuvant.

5. The composition of claim 1, said composition further comprising hepatitis viral pathogen-infected denatured tissue.

6. A hepatitis immunogen comprising heat denatured hepatitis virus type B and type C, wherein the hepatitis B virus and hepatitis C virus are denatured through a method comprising drying the hepatitis B virus and hepatitis C virus and denaturing the resulting dried viruses using heat alone to produce the immunogen, wherein the immunogen is formulated as an oral pill.

7. The immunogen of claim 6, wherein said immunogen is formulated without an immune adjuvant.

8. The immunogen of claim 6, wherein the immunogen comprised in said pill is between about 0.0000001% to about 20% by weight.

9. An oral composition suitable for inducing an immune response in a subject, the composition comprising a first component comprising denatured hepatitis type B or type C viral pathogen, wherein the pathogens are denatured through a method comprising drying the pathogen and denaturing the resulting dried pathogen using heat alone, and a second component comprising a denatured pooled blood tissue from a host infected by hepatitis virus type B and type C.

10. The oral composition of claim 9, said composition further comprising calcium or magnesium, or both.


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More details can be seen in the original link.








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StephenW

回复 batibaby 的帖子

It is still not clear what bits of the HBV virus are left intact in the vaccine. 目前尚不清楚乙肝病毒什么的部分保持不变在疫苗中。
But the most important question is: how does the vaccine work?但最重要的问题是：疫苗如何实现治愈?
Immune tolerance or immune booster? 免疫耐受或免疫助推器?
V5 did not address this question. V5没有解释这个问题.
Hope experts can give us some comments. 希望专家可以给我们一些意见。

batibaby

回复 StephenW 的帖子

仅仅从实用性来看，假如V-5的安全性能得到保证，并且高治愈率能在大规模的临床试验中重现的话，其治愈原理的研究到不是很急迫。

StephenW

回复 batibaby 的帖子

You are right. 你是正确的
If immune tolerance, the liver should last longer, but you will always be HbsAg positive.如果免疫耐受，肝应该持续较长时间，但你永远是乙肝表面抗原阳性.
If immune booster, a complete cure may be possible.如果免疫助推器，有完全治愈的可能.
The main point is that: the company has not done sufficient research, tests, and clinical trials to convince me that it is safe and effective.主要的一点是：该公司并没有做足够的研究，试验和临床试验，以说服我，这是安全和有效.
My personal opinion only.我个人的看法而已。

富贵数字

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