硝唑尼特的来源

lemonades

从HCV medhelp 转来的。加上HBV medhelp里面stefano170669战友的帖子和查找的信息，这个药治疗HBV的希望应该是相当大的。有可能是又一个阿德福韦和替诺福韦的故事。

建议抗病毒药都耐药的战友可以考虑一试，价格便宜，也不用考虑耐药和停药的问题。
Alinia (Nitazoxanide) Sources
by mike716, Dec 13, 2009 10:40PM
Hi, fellow medhelpers! At the risk of becoming a pest and annoying those who don't love me (yes, such people do seem to exist and they're not all doctors, I fearFears and phobias), I'm posting again. However, this is not a "give me" post, but a "giving back" post.

I spent some time recently searching for info on and sources of AliniaAlinia (one brand name), or nitazoxanide (the chemical name). I thought I'd share some of the information with you.

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First-testosterone mc, names. Nitazoxanide comes in so many different brand names that I can only list a few. AliniaAlinia was the first, and is the drug name given to nitazoxanide by its discoverer, Dr. Jean-Francois Rossignol, who works at the Pasteur Institute in Paris. The Pasteur Institute is where the AIDS virus was first isolated and identified (despite claims to the contrary by certain less-than-forthright persons at the National Institute of Health in Washington). Dr. Rossignol is part of a company called Romark Laboratories, in Tampa, Florida, which manufactures Alinia and is running the current trials for its use as an adjunct therapy with SOC.

Romark has licensed certain other manufacturers to produce nitazoxanide. These are the less-expensive equivalents that can be found, for example, in Europe and Canada and a few other places that still respect patents and copyrights. In places that don't, nitazoxanide is produced by a plethora of small-ish pharmaceutical companies under a myriad of brand names. A few of them are: Daxon, Dexidex, Pacovanton, Paramix, Nitax, Zox, Nitazox, Toza, Zóntricon, Celectan, Nixoran, Dexidex, Kidonax, Nitanid, Colufase, Nodik, Paraxin, Rosanil, Nitaxom, Noxolin, Uniplus7, Nitaxin, Nitapax, Zoxanid, Nitarid, Bionit, Rosanil, Parsenida, Zotanixin.

Who thinks up all these silly names? It makes you wonder...

Anyway, these are all nitazoxanide, or pretend to be. The ones that are manufactured in places where there isn't much control over pharmaceuticals might not be exactly the same formula as the nitazoxanide used in Alinia. On the other hand, it isn't a very complex chemical so there's really not much point in them using anything else (unless it's sugar or talc).

One point about the chemical contents that could be important, though, is that Romark appears to be using a time-release formulation of nitazoxanide in the Alinia used in their trials. I sincerely doubt that any of these other nitazoxanides are time-release.

Prices vary widely, as one would imagine. And since the Internet has spawned huge industries of online wholesalers, retailers, and geographically-unidentifiable resellers of everything under the sun including pharmaceuticals, there are places (I use this term in its broadest virtual sense) where you can buy nitazoxanide, or something that looks very much like it, for a small fraction of what the name brand companies sell it for. Here's a list of the ones I've had time to look at, together with price data:



===========================================

http://www.brandprescriptiondrugs.com/Nitazoxanide.htm   (Int'l comparison site)

Nitarid

Cipla Ltd. (India)

2 x 60 tabs x 500mg  $ 99.65  ($0.83/tablet)
   
===========================================

http://www.generics.ws/shopping_carts/show/

(India)

Nizonide
Lupin Pharm.

12 x 2 = 24 for $18.96  =  ($0.79/tablet)

===========================================

OnlinePharmaciesCanada.com

(Canada)

Generic 500mg 60 Tablets $73.79  ($1.23/tablet)

===========================================

http://www.farmasana.com.mx/productos.pdf

(Mexico)

Kidonax

65 pesos = 5USD /bottle of 6 x 500mg   ($0.83/tablet)

===========================================

Nitaxin - Qualifarm SA in Guatemala

(Guatemala)

6 tablets x 500mg  69 Quetzals = 8 USD ($1.33/tablet)

Teléfono: 2414 4242
Fax: 23371560
4ta. Avenida 19-33, zona 14
Guatemala, Guatemala

===========================================

http://patientindia.com/resultDe ... 7&brandId=10880

(India)

NIZONIDE   6  x  ? 45.36   Lupin Laboratories

===========================================

http://chemistparadise.com/Nizonide_500_mg-d-32183.html

(India)

Nizonide 500 mg
Name:   Nizonide
Manufacturer:   Lupin Laboratories Ltd. (Pinnacle)
Form:   Tablet
Dosage:   500 mg
Packing:   10
Chemical name:   Nitazoxanide
Price:   3.50 ($1.67/tablet)

Others:

Brand:   Manufacturer:   Dosage:   Price:   

Zimdax DT   US Vitamins Limited   200 mg   2.50
Mehulox   Heal All Pharmaceuticals (P) Ltd.   500mg   3.50
Mehulox DT   Heal All Pharmaceuticals (P) Ltd.   200mg   2.50
Nitacure   Alembic Chemical Works Co Ltd   200mg   3.67
Nitarid   Cipla Limited   500mg   6.25
Nitarid DT   Cipla Limited   200mg   4.42
Nitcol   Rexcel Pharmaceuticals   500mg   5.83
Nitcol DT   Rexcel Pharmaceuticals   200mg   4.17
Zstop   Svizera Healthcare (Sigma Division)   200mg   4.42
Nizonide   Lupin Laboratories Ltd. (Pinnacle)   500 mg   3.50
Nizonide DT   Lupin Laboratories Ltd. (Pinnacle)   200 mg   7.50
Zimdax DT (500 mg)   US Vitamins Limited   500 mg   3.50
Zoxakind   Mankind Pharmaceuticals Pvt. Ltd.   500 mg   5.0

Chemical4u Ltd.
26 Parkridge Road
Ward Hill, Mumbai 01835 India
Catalog sales: +91-800-343-0660 or 978-521-6300
Bulk/Specialty Sales: +91-888-343-8025
***@****
FAX:           +91 101 889 9898

===========================================

http://www.mexmeds4you.com/productdetails.asp?pid=1886

(Mexico)

Nitazoxinide Generic - 500 mg
Package Size: 6 tabs
Price: $10  ($1.67/tablet)

===========================================

http://www.progressiverx.com/sto ... e=search&page=1

(Canada)

Alinia (Nitazoxanide)

60 Pills x 500 mg  $71.99   ($1.20/tablet)

===========================================


Whew! There sure is a lot of nitazoxanide around. And it seems to be getting cheaper by the minute.

Now, some of these companies (I use the term loosely) may require a prescription, or say they do. Others don't. Still others make believe they do but give you unusual ways of showing you've got one, like emailing a scan of a prescribed bottle label! People need to investigate these details and deal with them individually (like most other things in this sad, strange world).

I hope this info is of some use. I personally believe that nitazoxanide has been shown to work and that it beats doing SOC alone, especially for us gt1 infectees. Being gt1, 65 years old, and having a high viral load and low platelets, I figure my chances of SVRing with SOC are around 20%. So I'm not going to Tx with just SOC, I'll add nitazoxanide. It makes sense.

Cheers!

Mike

[ 本帖最后由 lemonades 于 2010-3-14 13:19 编辑 ]

lemonades

此作者说，有的公司会要求你出示处方，但有些不需要，总之还是很有希望弄到。都是以美元为单位的。

保险的说，那些抗病毒药都耐药的战友的确值得一试。

lemonades

给大家一个可以直接买的网址http://www.thepharmacyexpress.com/Products2.asp?ID=4121&T=a

因为我不在国内，所以不知道国内的怎么汇款，但是大家可以试试。两个月大概100美金的样子，这个是很便宜的，怀疑药品质量的可以到加拿大的药店买，叫Alinia，最贵，大概贵一倍。

PS：我不是打广告，也并不鼓励所有战友都去试，只是给所有核苷类都耐药和不能打干扰的战友一个可供参考的选择。

因为HCV的临床试验已出，加上此药早就被批准，所以我才敢发这个帖子。

居心叵测者请嘴下积德。否则讲道理和药理，你定讲不过我。当然，无良小人不在我计较的范围内。

mtv982

谢谢侠女!以后耐药了多了一条路.

自杀未遂

lemonades还是可以信赖的

lemonades

我还没抗过病毒，但我准备来试硝唑尼特了，先去找医生开，因为他开我可以报销70％，他若不同意我就自己买算了。

lemonades

因为现在在吃补中益气丸止腹泻，睡眠也有好转，所以查了下文献。
居然发现好多试验是日本人做的，还写是传统的日本药，看着心寒。
中国人也有做的，但没有集中在免疫方面。

lemonades

我现在是想先试硝唑尼特一个月，用DNA指标监控，有好转就继续用，无用但如果也没副作用，或许考虑用2个月，实在没用就考虑上TNF。反正用了这个不影响TNF。

mtv982

关注,期待你的成功.

lemonades

现在还只是在跟医生联系中，如果我吃上了，我会定期来汇报感受，给战友一点借鉴。