当前乙肝治疗方法

旋干转坤

Current Therapy of Chronic Hepatitis B
国外的一篇文献，感觉还是挺有用的，我就把结论贴过来。附件是全文，想看的自己下载看看吧！版主觉得好的话帮忙置顶吧，谢谢啦！
Conclusions
If there are no contraindications, the treatment of choice for either HBeAg or anti-HBe chronic hepatitis B-naı¨ve patients is PEG-IFN alfa 2a or 2b administered for 48 weeks due to its higher response rate and sustained remission in comparison with nucleoside/nucleotide analogs (Table 1). Nucleoside/nucleotide analogs can be useful in naı¨ve patients when failure of PEG-IFN alfa therapy has been observed.
If there are contraindications to administer PEG-IFN alfa in naı¨ve patients, entecavir is the treatment of choice due to its similar antiviral efficacy in comparison with other analogues and its lack of appearance of resistant mutants and low secondary effects.
Due to the high frequency of appearance of resistant mutants with lamivudine, this drug should not be used in chronic hepatitis B treatment-naı¨ve patients (Table 2).
In patients under lamivudine treatment who develop resistant mutants, this drug should be maintained and adefovir should be added in order to achieve antiviral response.In the case of resistant mutant to adefovir or entecavir, tenofovir rescue therapy may be useful, although future studies with a large number of patients should be conducted.
In the future, the combination of PEG-IFN alfa with more than one nucleoside analog or triple combination of nucleoside analogues should be studied in resistant chronic hepatitis B.

[ 本帖最后由 旋干转坤 于 2009-12-16 13:49 编辑 ]

孤寂百年

旋干转坤

跟你说，我没必要炫耀什么英文，我英文也不是很好，但是这篇文章的英文确实不难，你没有看就不要瞎说。现在回答你下面的两个建议：1、翻译成中文，可以，把结论部分那几段话翻译成中文没什么问题，我有时间的时候可以翻，但是整篇文章17页，也要我全部翻译吗？2、你自己爱看就看，不爱看就从哪里来，回哪里去，没有强求你看，我只是觉得有用，转上来，没有你那么无聊！

fssdcc

楼主不用理会其他人!能够找来这些资料,非常感谢楼主!如果需要翻译,可短消息联系版主特深沉!

旋干转坤

文中的表1，中英文的都发上来吧，关于各种抗病毒药效果的比较。

[ 本帖最后由 旋干转坤 于 2009-12-16 10:17 编辑 ]

走遍四方

不容易。谢谢啦。大家都不容易。。。

duqingwu2001

谢谢了。。。。

班长

替诺福苇是啥
好像效果最好？？？？

janehmh

收下了以备后

马星华

同楼上，那个表可以参考下。