15/10/02说明:此前论坛服务器频繁出错,现已更换服务器。今后论坛继续数据库备份,不备份上传附件。

肝胆相照论坛

 

 

肝胆相照论坛 论坛 学术讨论& HBV English 给战友点希望--硝唑尼特治疗慢肝
楼主: 闹心啊
go

给战友点希望--硝唑尼特治疗慢肝   [复制链接]

Rank: 9Rank: 9Rank: 9

现金
17064 元 
精华
12 
帖子
9399 
注册时间
2007-6-26 
最后登录
2017-11-25 

风雨同舟

541
发表于 2010-2-18 10:32 |只看该作者
日行一善(百善孝为先)

Rank: 9Rank: 9Rank: 9

现金
9671 元 
精华
帖子
12248 
注册时间
2009-10-14 
最后登录
2021-11-25 

神仙眷侣 如鱼得水 翡翠丝带 健康之翼

542
发表于 2010-2-18 11:11 |只看该作者
原帖由 lemonades 于 2010-2-16 14:09 发表
就因为我是学药的,所以我才说不用找专业人士了。

至于那剩下的1%是多少,其中肯定有水,然后就看这个合成步骤,最后一步都是些什么成分?那么这个粉末里面就多少有最后一步的一些成分,版上清除cccDNA就是学合成的,他说他可以全 ...


你的链接在哪里?
温故中知新

Rank: 9Rank: 9Rank: 9

现金
17064 元 
精华
12 
帖子
9399 
注册时间
2007-6-26 
最后登录
2017-11-25 

风雨同舟

543
发表于 2010-2-18 11:47 |只看该作者
原帖由 走遍四方 于 2010-2-18 11:11 发表


你的链接在哪里?

硝唑尼特的来源
从HCV medhelp 转来的。加上HBV medhelp里面stefano170669战友的帖子和查找的信息,这个药治疗HBV的希望应该是相当大的。有可能是又一个阿德福韦和替诺福韦的故事。

建议抗病毒药都耐药的战友可以考虑一试,价格便宜,也不用考虑耐药和停药的问题。
Alinia (Nitazoxanide) Sources
by mike716, Dec 13, 2009 10:40PM
Hi, fellow medhelpers! At the risk of becoming a pest and annoying those who don't love me (yes, such people do seem to exist and they're not all doctors, I fearFears and phobias), I'm posting again. However, this is not a "give me" post, but a "giving back" post.

I spent some time recently searching for info on and sources of AliniaAlinia (one brand name), or nitazoxanide (the chemical name). I thought I'd share some of the information with you.

FirstFirst progesterone mc10
First progesterone mc5
First-progesterone vgs 100
First-progesterone vgs 200
First-progesterone vgs 25
First-progesterone vgs 400
First-progesterone vgs 50
First-testosterone
First-testosterone mc, names. Nitazoxanide comes in so many different brand names that I can only list a few. AliniaAlinia was the first, and is the drug name given to nitazoxanide by its discoverer, Dr. Jean-Francois Rossignol, who works at the Pasteur Institute in Paris. The Pasteur Institute is where the AIDS virus was first isolated and identified (despite claims to the contrary by certain less-than-forthright persons at the National Institute of Health in Washington). Dr. Rossignol is part of a company called Romark Laboratories, in Tampa, Florida, which manufactures Alinia and is running the current trials for its use as an adjunct therapy with SOC.

Romark has licensed certain other manufacturers to produce nitazoxanide. These are the less-expensive equivalents that can be found, for example, in Europe and Canada and a few other places that still respect patents and copyrights. In places that don't, nitazoxanide is produced by a plethora of small-ish pharmaceutical companies under a myriad of brand names. A few of them are: Daxon, Dexidex, Pacovanton, Paramix, Nitax, Zox, Nitazox, Toza, Zóntricon, Celectan, Nixoran, Dexidex, Kidonax, Nitanid, Colufase, Nodik, Paraxin, Rosanil, Nitaxom, Noxolin, Uniplus7, Nitaxin, Nitapax, Zoxanid, Nitarid, Bionit, Rosanil, Parsenida, Zotanixin.

Who thinks up all these silly names? It makes you wonder...

Anyway, these are all nitazoxanide, or pretend to be. The ones that are manufactured in places where there isn't much control over pharmaceuticals might not be exactly the same formula as the nitazoxanide used in Alinia. On the other hand, it isn't a very complex chemical so there's really not much point in them using anything else (unless it's sugar or talc).

One point about the chemical contents that could be important, though, is that Romark appears to be using a time-release formulation of nitazoxanide in the Alinia used in their trials. I sincerely doubt that any of these other nitazoxanides are time-release.

Prices vary widely, as one would imagine. And since the Internet has spawned huge industries of online wholesalers, retailers, and geographically-unidentifiable resellers of everything under the sun including pharmaceuticals, there are places (I use this term in its broadest virtual sense) where you can buy nitazoxanide, or something that looks very much like it, for a small fraction of what the name brand companies sell it for. Here's a list of the ones I've had time to look at, together with price data:

===========================================

http://www.wisemeds.net/buy_online/Nitarid.shtml
***@****

Nitarid
Glenmark Ltd.
500mg x 60 Tablets  $55.42  ($0.92/tablet)

===========================================

http://www.brandprescriptiondrugs.com/Nitazoxanide.htm   (Int'l comparison site)

Nitarid

Cipla Ltd. (India)

2 x 60 tabs x 500mg  $ 99.65  ($0.83/tablet)
   
===========================================

http://www.generics.ws/shopping_carts/show/

(India)

Nizonide
Lupin Pharm.

12 x 2 = 24 for $18.96  =  ($0.79/tablet)

===========================================

OnlinePharmaciesCanada.com

(Canada)

Generic 500mg 60 Tablets $73.79  ($1.23/tablet)

===========================================

http://www.farmasana.com.mx/productos.pdf

(Mexico)

Kidonax

65 pesos = 5USD /bottle of 6 x 500mg   ($0.83/tablet)

===========================================

Nitaxin - Qualifarm SA in Guatemala

(Guatemala)

6 tablets x 500mg  69 Quetzals = 8 USD ($1.33/tablet)

Teléfono: 2414 4242
Fax: 23371560
4ta. Avenida 19-33, zona 14
Guatemala, Guatemala

===========================================

http://patientindia.com/resultDe ... 7&brandId=10880

(India)

NIZONIDE   6  x  ? 45.36   Lupin Laboratories

===========================================

http://chemistparadise.com/Nizonide_500_mg-d-32183.html

(India)

Nizonide 500 mg
Name:   Nizonide
Manufacturer:   Lupin Laboratories Ltd. (Pinnacle)
Form:   Tablet
Dosage:   500 mg
Packing:   10
Chemical name:   Nitazoxanide
Price:   3.50 ($1.67/tablet)

Others:

Brand:   Manufacturer:   Dosage:   Price:   

Zimdax DT   US Vitamins Limited   200 mg   2.50
Mehulox   Heal All Pharmaceuticals (P) Ltd.   500mg   3.50
Mehulox DT   Heal All Pharmaceuticals (P) Ltd.   200mg   2.50
Nitacure   Alembic Chemical Works Co Ltd   200mg   3.67
Nitarid   Cipla Limited   500mg   6.25
Nitarid DT   Cipla Limited   200mg   4.42
Nitcol   Rexcel Pharmaceuticals   500mg   5.83
Nitcol DT   Rexcel Pharmaceuticals   200mg   4.17
Zstop   Svizera Healthcare (Sigma Division)   200mg   4.42
Nizonide   Lupin Laboratories Ltd. (Pinnacle)   500 mg   3.50
Nizonide DT   Lupin Laboratories Ltd. (Pinnacle)   200 mg   7.50
Zimdax DT (500 mg)   US Vitamins Limited   500 mg   3.50
Zoxakind   Mankind Pharmaceuticals Pvt. Ltd.   500 mg   5.0

Chemical4u Ltd.
26 Parkridge Road
Ward Hill, Mumbai 01835 India
Catalog sales: +91-800-343-0660 or 978-521-6300
Bulk/Specialty Sales: +91-888-343-8025
***@****
FAX:           +91 101 889 9898

===========================================

http://www.mexmeds4you.com/productdetails.asp?pid=1886

(Mexico)

Nitazoxinide Generic - 500 mg
Package Size: 6 tabs
Price: $10  ($1.67/tablet)

===========================================

http://www.progressiverx.com/sto ... e=search&page=1

(Canada)

Alinia (Nitazoxanide)

60 Pills x 500 mg  $71.99   ($1.20/tablet)

===========================================


Whew! There sure is a lot of nitazoxanide around. And it seems to be getting cheaper by the minute.

Now, some of these companies (I use the term loosely) may require a prescription, or say they do. Others don't. Still others make believe they do but give you unusual ways of showing you've got one, like emailing a scan of a prescribed bottle label! People need to investigate these details and deal with them individually (like most other things in this sad, strange world).

I hope this info is of some use. I personally believe that nitazoxanide has been shown to work and that it beats doing SOC alone, especially for us gt1 infectees. Being gt1, 65 years old, and having a high viral load and low platelets, I figure my chances of SVRing with SOC are around 20%. So I'm not going to Tx with just SOC, I'll add nitazoxanide. It makes sense.

Cheers!

Mike
日行一善(百善孝为先)

Rank: 4

现金
219 元 
精华
帖子
66 
注册时间
2010-2-4 
最后登录
2017-11-20 
544
发表于 2010-2-18 12:28 |只看该作者
我看不明白啦

Rank: 4

现金
288 元 
精华
帖子
180 
注册时间
2008-9-16 
最后登录
2016-9-8 
545
发表于 2010-2-18 13:28 |只看该作者
我看到战友们有人以身试药,非常感动,就是想问下,狗政府们都在干什么,从中央到地方的狗官们都干什么吃去了

Rank: 6Rank: 6

现金
1537 元 
精华
帖子
870 
注册时间
2007-11-2 
最后登录
2016-5-22 
546
发表于 2010-2-18 13:36 |只看该作者
原帖由 绝望的死神 于 2010-2-18 13:28 发表
我看到战友们有人以身试药,非常感动,就是想问下,狗政府们都在干什么,从中央到地方的狗官们都干什么吃去了

这个。。。只是为了自己早日摆脱乙肝,谈不上奉献,虽然结果对大家有参照作用。。。
那杀不死我的,使我变的更强
只有你我才懂得不可思议
这注定是一场持久的大战,有人死去,有人活下来。尘封我的忧伤,一直到坟墓里,默默是你的坚强;长久的并肩已经使我们能在无言的相视中心意相通;回首万里征途,醉爱夕阳美。

Rank: 7Rank: 7Rank: 7

现金
4537 元 
精华
帖子
1886 
注册时间
2009-8-29 
最后登录
2018-2-4 
547
发表于 2010-2-18 13:38 |只看该作者


祝成功!!
绝望中探索希望

Rank: 7Rank: 7Rank: 7

现金
3916 元 
精华
帖子
2165 
注册时间
2010-1-10 
最后登录
2012-6-27 
548
发表于 2010-2-18 14:27 |只看该作者
原帖由 绝望的死神 于 2010-2-18 13:28 发表
我看到战友们有人以身试药,非常感动,就是想问下,狗政府们都在干什么,从中央到地方的狗官们都干什么吃去了

这个要问他们去 .这世道就是这样 有利益的争先恐后  没利益的不管死活 死了后才重视  大地震死那么多人 那8方就支援了      这YG算什么 反正他们身体很健康

Rank: 7Rank: 7Rank: 7

现金
3916 元 
精华
帖子
2165 
注册时间
2010-1-10 
最后登录
2012-6-27 
549
发表于 2010-2-18 15:05 |只看该作者
原帖由 生命满希望 于 2009-10-15 11:29 发表
2006年已经有此消息出现,但几年过去也没用在临床,估计是假的!

到现在已经4年了 说丙肝2期临床了, 不知道真假,  也不见得人家说效果怎样

Rank: 9Rank: 9Rank: 9

现金
17064 元 
精华
12 
帖子
9399 
注册时间
2007-6-26 
最后登录
2017-11-25 

风雨同舟

550
发表于 2010-2-18 16:33 |只看该作者
原帖由 山东小兵 于 2010-2-18 13:36 发表

这个。。。只是为了自己早日摆脱乙肝,谈不上奉献,虽然结果对大家有参照作用。。。

日行一善(百善孝为先)
‹ 上一主题|下一主题
你需要登录后才可以回帖 登录 | 注册

肝胆相照论坛

GMT+8, 2024-9-20 07:03 , Processed in 0.029701 second(s), 11 queries , Gzip On.

Powered by Discuz! X1.5

© 2001-2010 Comsenz Inc.