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又来了，王宝恩同志，在宁夏下放的时候就搞这个复方861，中西医结合，到头来根本没有什么眉目。虽然以英文发表了不少论文（他也不容易了，80多了，不是党票早就被离退办公室请走了）。 但是国际审核这些以英文发表的文献时候发现，他们根本不能进入临床，缺乏确实数据和科学循证证据...
这是发表在"临床消化和肝脏学" 名为 “使用草药补充物治疗慢性肝病” 一文的文摘：
Use of herbal supplements for chronic liver disease
Clinical Gastroenterology and Hepatology, Volume 2, Issue 11, Pages 947-956
C.Levy, L.Seeff, K.Lindor
Abstract
Background & Aims: Complementary and alternative medicine (CAM) is becoming popular among patients with liver disease. Although there is a growing body of evidence regarding potential mechanisms of action of these and other herbs, caution must be used to interpret the results of the few clinical trials available. Our goal was to discuss the biologic rationale for the use of specific herbs (silymarin, glycyrrhizin, sho-saiko-to, Phyllanthus amarus, Picrorrhiza kurroa, Compound 861, CH-100, and LIV.52) in the treatment of chronic liver diseases, as well as the evidence for their efficacy and adverse effects according to clinical trials. Methods: Because of the relative paucity of clinical studies using herbs, every trial published in English was reviewed. Results: Although many trials suggest that these herbs can decrease serum transaminase levels, the effects on hepatic histopathology and long-term survival are either poorly studied or conflicting. LIV.52 has been withdrawn from the market because of deleterious effects in patients with liver disease. Conclusions: Based on current evidence, we cannot recommend the use of herbal supplements for the routine treatment of any chronic liver disease and further well-designed clinical trials are necessary.
摘要
背景与目的：补充和替代医学（ CAM）在肝病患者中正在成为时髦的事物。虽然，就这些草药有逐多可能存在的机制作用的证据，但我们必须用谨慎来解释其结果，因很少有临床试验存在。我们的目标是从生物理由讨论使用特定的草药（水飞蓟素，甘草酸，郑硕柴胡汤的，苦味叶下珠， Picrorrhiza kurroa ，复方861 （王宝恩的），一架CH - 100 ，和LIV.52 ）治疗慢性肝病，以及根据临床试验来说明证据的有效性和负面影响。方法：由于相对缺乏使用草药的临床研究，我们就对每个以英文出版（“研究文献”）的研究进行了审查。结果：虽然许多试验表明，这 些中药可以降低血清转氨酶水平的影响，但对肝组织病理学和长期生存缺乏研究或研究的很差，或相互矛盾。 LIV.52已经退出了市场，因为有害，影响患者的肝脏疾病。结论：根据目前的证据，我们不能建议使用草药补充剂作为对任何一种慢性肝病的常规治疗，而进一步科学完满 设计的 临床试验是必要的。
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肝硬化患者已经很惨了，而且有的很严重，怕的就是误导。 请别再让他们踏上歧途害了自己的生命了！ |
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发表于 2009-6-26 14:26
