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发表于 2002-6-22 05:44
Re:please
First, if your husband's LFTs was normal at the time the Chinese doctor Rx-ed Lamivudine, the doctor was wrong. One must have both elevated liver function test and HBV DNA in order to get the best result for trement.
Second, Lamivudine has been approved for treatment of chronic hepatitis B in Canada. The reasons his doctor didn't check his HBV DNA were probably because your husband didn't fit the lamivudine treatment since his ALT was normal, he had a positive HBVeAg, and there is no need for checking of viral load.
Third, I think you have to tell his doctor or a heptologist that your husband was on Lamivudine when he was in China; ask the doctor to consider and seek his help on: your husband needs to check his viral load and HBeAg to make sure there is no drug resistance or viral mutation occurred, he needs no interruption of Lamivudine treatment for at least some time since he has already been on the medication;
Else, you have to switch the doctor if it is possible with your helath insurance provider, or drive down to Mexico to make the illegal purchase, but you still face the problem of viral mutation, and board inspection; so the only way is to let his doctor to know and understand the story;
hope this helps and all is well.
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