维他命E能辅助治疗乙肝么？

两两相忘929

Can Vitamin E Help People Recover From Hepatitis B?
维他命E能辅助治疗乙肝么
June 19, 2001
2001年6月19日
http://www.thebody.com/摘录
neolinguist翻译
Background
背景
When someone is first infected with the microbe HBV -- hepatitis B virus -- it causes inflammation of the liver. Some people can recover from HBV infection, but in people who are not able to recover the virus causes ongoing liver damage, slowly destroying the liver. In some cases, HBV infection eventually leads to liver cancer. Although drugs such as interferon-alpha and 3TC (Epivir, lamivudine) can help some people recover, the majority of people treated with these drugs do not experience a sustained recovery (their recovery is only temporary). Researchers are testing combinations of other drugs to assess their long-term effectiveness.
乙肝病毒感染病人之后就导致肝脏炎症的发作。其中某些病人可以自我康复痊愈而另一些病人的肝脏持续的受到炎症的危害，严重的最终会导致肝癌。虽然干扰素-α（interferon-alpha）与 3TC (Epivir lamivudine，拉米夫定,)此类药物能帮助病人康复，但这些药物对大部分病人的治疗效果仅仅是暂时性的。研究人员在测试其它药物的长期效用。
Meanwhile researchers in Bologna, Italy, have been studying the impact of vitamin E on the HBV infection for several years. The researchers chose this nutrient because it may protect the liver from damage associated with HBV infection and it may also enhance the immune system's ability to fight the virus. Preliminary results from experiments on people with HBV by these researchers suggested that 600 mg/day of vitamin E was safe and useful in some people with HBV. We now present their results from a larger study.
意大利.波洛尼亚的研究人员评估维他命E对乙肝病人的效用已有多年。维他命E不但能够保护肝脏而且可以提高人体免疫力以便自身抵抗乙肝病毒。初期的研究表明每天600mg的维他命E摄入量对某些乙肝病人的治疗是有效且安全的。以下为研究的具体细节：

Study Details
研究细节
Researchers recruited 32 subjects (8 female, 24 male) who had HBV detected in samples of their liver and blood. As well, all subjects had higher-than-normal levels of the liver enzyme ALT (alanine aminotransferase) for at least six months, suggesting ongoing liver damage. No subject tested positive for HIV or for hepatitis C virus. Before entering this study, 23 subjects had received treatment with interferon-alpha for HBV but it did not work. Doctors randomly assigned 15 subjects to receive 300 mg of vitamin E twice daily for three months. The remaining 17 subjects received no treatment and served as a control or comparison group. At the end of three months, subjects were monitored for 12 more months.
研究人员邀请了32名研究对象（8为女士，24位男生）做测试。（在他们的血液中测得乙肝病毒）。以上的各位在至少6个月中转氨酶偏高—即乙肝受到持续的损害。在未参与此调查之前，其中的23位都曾今用过干扰素-(interferon-alpha)但无效果。医生抽取了15位人员，嘱咐他们三个月内每日摄入两次维他命E，摄入量为300mg。其它的17位人员归为对比组不做任何治疗。在三个月之后，继续观察12个月。

Results
结果
By the end of the study (month 15), 47% of subjects in the vitamin E group and 0% in the control group had recovered from HBV infection. This difference in recovery between the two groups was statistically significant, that is, not likely due to chance alone.
在测试之后（历时15个月），47%服用维他命的人员康复，0%的对比组人员康复。如此大的统计差异不太可能仅仅是出于偶然。
Four subjects stopped taking vitamin E by the second month of the study because their liver enzyme levels rose to more than 10 times the upper limit of normal. The research team reported no side effects due to vitamin E.
由于转氨酶偏高（10倍于正常上限），4个维他命服用人员在第二个月停止服用维他命E。研究人员认为维他命E没有任何副作用。

Delayed Recovery?
复原迟疑（迟来的治疗效果）？
The research team found that in the vitamin E group there appeared to be a "delayed response" to treatment. They noted that levels of HBV continued to decline over time, especially after the third month, when subjects stopped taking vitamin E. The researchers stated that this type of response does not usually occur with the use of anti-HBV drugs such as 3TC. But it has been reported in clinical trials of the immune booster thymosin-alpha1 (Zadaxin) for HBV.
研究人员发现有些服用维他命人员治疗效果姗姗来迟。乙肝病毒的数量随着时间减少，特别是第三个月有些人员停止服用维他命之后，效果更是明显。3TC药物没有此类效果但thymosin-alpha1（提高免疫力药品）又类似的效果。
Further studies need to be done by other researchers to confirm these findings in a larger number of subjects. As well, although no subject in this study had HIV, we hope that other research teams will test the impact of vitamin E -- with and without anti- HBV drugs -- in people who are co-infected with HIV and HBV.
需做进一步的研究确认以上结论。虽然以上人员不带有艾滋病毒，我方希望其它的研究团队能够测试维他命E对艾滋病乙肝双患者的治疗效用。

看到一片报道，希望给给我战友一个参考价值。