- 现金
- 1498 元
- 精华
- 1
- 帖子
- 653
- 注册时间
- 2002-6-16
- 最后登录
- 2007-2-2
|
Scientists find gene for intelligence
by Steve Connor
Science
Correspondent
THE FIRST gene linked with high intellectual ability has been found by
scientists. The discovery could herald the development of genetic
tests for young children to identify high-flyers.
The gene has been found by a team headed by Professor Robert Plomin, a
leading behavioural geneticist at the Institute of Psychiatry in
London.
He discovered it by comparing the DNA of several groups of about 50
people who scored well above average on a range of IQ tests.
Details of the research are expected to be revealed this week at an
international conference on psychiatric genetics in Santa Fe in New
Mexico.
Plomin refused to comment on his findings in detail, but it is
understood that the scientists believe the gene may account for about
2% of the variation in intelligence between individuals when they are
compared through IQ tests.
Although this may appear to be only a marginal difference, it is only
one gene that has been discovered and researchers believe there will
be others. The fact that a link has been established will be regarded
as a significant breakthrough by the scientific community.
Commentators believe the gene resides on chromosome 6, one of the 23
pairs of chromosomes that form the human genetic blueprint.
Plomin's study involved more than 300 people split into separate
groups depending on their intellectual ability. Some had very high
IQs, some were average and others scored well in certain intellectual
pursuits such as mathematics and verbal ability.
Cells taken from each of them were stored as permanently living
cultures so that DNA could be taken and analysed at any time in the
future in order to isolate any other genes that may be implicated in
high intelligence.
Plomin said it would be possible to understand more about inherited
defects in intelligence by studying the normal range of intellectual
ability, including those people who are exceptionally gifted.
He believes that the genetic component of intelligence may be
determined by a number of different genes, possibly 100, with some
being more important than others.
The research, however, has been controversial, with eminent scientists
saying it would be unethical to carry out the work without discussing
its implications more widely with the public.
Professor Peter Harper, director of the Institute of Molecular
Medicine in Cardiff, wrote an open letter in 1995 to the journal
Behaviour Genetics arguing that the research could lead to genetic
screening of embryos and foetuses for "intelligence genes" without an
adequate scientific basis.
As a result of the outcry, the Medical Research Council said it would
consult the public more widely before giving Plomin several million
pounds in research grants to carry out a large study on identical and
non-identical twins.
Plomin wants to collect the DNA of all twins born between 1994 and
1996 and relate genetic and environmental differences to any mild
mental impairment. If it goes ahead, it will be the biggest twin study
ever undertaken in Britain and could take several decades to complete.
Plomin showed earlier this year that genes appear to be more important
in explaining differences in intelligence in older people than
environmental influences. "Education has greatly improved their
intelligence, but the differences among them . . . are largely due to
genetic differences," he said.
|
|