没有中文的,自己翻译.翻译了第一段,请指正? Chapter 1 Introduction Epidemiology of hepatitis B The hepatitis B virus (HBV) is one of the world’s most common infectious pathogens and has infected at least 2 billion of the global population. Current indications suggest that 350 million individuals have chronic infection and are at risk of death from liver disease. Hepatitis B is the tenth leading cause of death worldwide, and is responsible for over 1 million deaths every year due to cirrhosis of the liver and liver cancer. The prevalence of HBV infection varies worldwide, with areas of high endemicity in sub-Saharan Africa, the Pacific basin, the Amazon basin and Asia. There are a lower percentage of carriers in North America, Western Europe and Australia (Table 1-1). Up to 80% of primary liver cancer is attributed to HBV and there is a strong correlation between the prevalence of HBV carriers and the incidence of hepatocellular carcinoma (HCC) (Figure 1-1). Transmission of hepatitis B virus Hepatitis B virus is present in the blood, saliva, sweat, tears, breast milk and semen of infected individuals. It is a resilient virus, resistant to breakdown and able to survive 第一章 绪论 乙肝的流行病学 乙肝病毒(HBV)世界上很普遍的传染性病原体,全球至少有20亿人被感染. 最近有迹象表明,有3.5亿人,由于慢性感染,面临肝病导致的死亡. 全球每年有1百万以上的人死于肝硬化和肝癌, 大约1/10的重要原因是乙肝病毒引起的. 乙肝传染病的流行性有高度的地域特性, 亚马逊河盆地,太平洋盆地和亚洲是高发地区.北美,西欧和澳大利亚感染者比例比较低. (Table 1-1) 80%以上的原发性肝癌与HBV有关,HBV病毒与肝细胞癌变有很大的相关性. 乙肝病毒可以通过被感染者的血液,唾液,汗液,乳汁,眼泪和精液传播. 它有较强的抵抗性和生存能力. |