成人活體肝移植的優越長期結果

StephenW

成人活體肝移植的優越長期結果

肝移植

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     本研究比較了在加拿大單一中心接受活體肝移植 (LDLT) 的 668 名患者與接受死者供體肝移植 (DDLT) 的 1596 名患者的 20 年結果。 總體而言，LDLT 組更年輕，男性患者比例更高，自身免疫性肝炎患病率更高。 LDLT 組在移植時住院的可能性也較小，移植時的 MELD 評分較低。 多變量分析顯示，LDLT 和 DDLT 組對患者和移植物存活的危害相似。

     LDLT 是一種有效的治療選擇，其患者和移植物存活率與 DDLT 相似。 LDLT 還可以減少 LT 的等待時間。
Superior Long-Term Outcomes of Adult Living Donor Liver Transplantation

Liver Transplantation

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    This study compared the 20-year outcomes of 668 patients who underwent living donor liver transplantation (LDLT) with those of 1596 patients who underwent deceased donor liver transplantation (DDLT) in a single center in Canada. Overall, the LDLT group was younger, had a higher proportion of male patients, and had a higher prevalence of autoimmune hepatitis. The LDLT group was also less likely to be hospitalized at the time of transplantation and had lower MELD scores at transplantation. Multivariable analysis revealed that the LDLT and DDLT groups had similar hazards of patient and graft survival.

    LDLT is an effective therapeutic option that has similar patient and graft survival rates as DDLT. LDLTs can also reduce waiting times for LT.

https://aasldpubs.onlinelibrary. ... df/10.1002/lt.26386