白蛋白-胆红素-血小板评分预测代偿期肝硬化患者高危食管静

StephenW

白蛋白-胆红素-血小板评分预测代偿期肝硬化患者高危食管静脉曲张

Abd elbaser，艾尔赛德·萨达；沙拉夫，艾哈迈德·洛菲亚；阿拉格法拉格 A.b
作者信息
欧洲胃肠病学和肝病学杂志：2022 年 3 月 - 第 34 卷 - 第 3 期 - 第 332-337 页
doi: 10.1097/MEG.0000000000002270

   
抽象的
背景

尽管内窥镜检查是在代偿期肝硬化患者中筛查高危静脉曲张 (HRV) 的金标准，但它具有侵入性、成本高且并非对所有患者都是必需的。因此，无创检查可以代替内窥镜检查。我们旨在评估白蛋白-胆红素-血小板 (ALBL-PLT) 评分作为预测代偿期肝硬化患者 HRV 与 Baveno VI 和扩展 Baveno VI 标准的无创测试。
方法

包括代偿期肝硬化患者（n = 204）。进行了实验室参数、食管胃十二指肠镜检查（EGD）和瞬时弹性成像测量肝脏硬度。根据 HRV 的状态对患者进行分类。我们根据 ALBL-PLT 评分、Baveno VI 和扩展的 Baveno VI 标准比较了两组。
结果

在所有患者中，96/204 (47%) 名患者患有 HRV。他们的肝脏硬度测量值高于没有 HRV 的人（33 ± 13.1 对 19.3 ± 8.25，CI，-19.94，-7.31，P 值 <0.001）。此外，所有 HRV 患者的 ALBL-PLT 评分均大于 3。ALBL-PLT 评分的受试者工作特征曲线下面积高于 Baveno VI 和扩展 Baveno VI 标准（分别为 0.894 对 0.722 和 0.792 ）。
结论

ALBL-PLT 评分大于 3 分对预测代偿期肝硬化患者的 HRV 具有良好的预测价值。
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StephenW

Prediction of high-risk esophageal varices in patients with compensated cirrhosis using albumin-bilirubin-platelet score

Abd elbaser, Elsayed Saada; Sharaf, Ahmed Lotfya; Farag, Alaa A.b
Author Information
European Journal of Gastroenterology & Hepatology: March 2022 - Volume 34 - Issue 3 - p 332-337
doi: 10.1097/MEG.0000000000002270

   
Abstract
Background

Despite the fact that endoscopy is the gold standard for screening of high-risk varices (HRVs) in patients with compensated cirrhosis, it is invasive, costly and not necessary for all patients. So, noninvasive tests can replace endoscopy. We aimed at evaluating the albumin-bilirubin-platelet (ALBL-PLT) score as a noninvasive test in predicting HRVs in compensated cirrhotic patients versus Baveno VI and extended Baveno VI criteria.
Methods

patients with compensated cirrhosis (n = 204) were included. Laboratory parameters, esophagogastroduodenoscopy (EGD) and liver stiffness measurement by transient elastography were done. Classification of patients according to the status of HRVs was done. We compared both groups on the basis of ALBL-PLT score, Baveno VI and extended Baveno VI criteria.
Results

Among the total patients, 96/204 (47%) patients had HRVs. They have higher liver stiffness measurement than those without HRVs (33 ± 13.1 versus 19.3 ± 8.25, CI, −19.94, −7.31, P value <0.001). Also, all HRVs patients have an ALBL-PLT score of more than 3. The area under the receiver operating characteristic curve for the ALBL-PLT score is higher than that for Baveno VI and extended Baveno VI criteria (0.894 versus 0.722 and 0.792, respectively).
Conclusion

ALBL-PLT score of more than three has a good predictive value in predicting HRVs among compensated cirrhotic patients.
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