新型透析机可逆转肝衰竭

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2021 年 8 月 13 日
新型透析机可逆转肝衰竭
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Banwari Agarwal, MBBS, MD

根据一项早期国际多中心研究的结果，对于患有急性慢性肝功能衰竭的人来说，希望可能即将来临。

研究人员发现，新型肝透析装置 DIALIVE 在这组患者中是安全有效的，显着增加了从器官衰竭中恢复的比例并缩短了恢复所需的时间。

“DIALIVE 是一种机械肝脏装置，它触及我们认为导致急性和慢性肝功能衰竭患者进一步器官衰竭的两个最重要的病理生物学机制的核心，”医学博士、MBBS 医学博士 Banwari Agarwal 说。伦敦皇家自由医院重症监护医学顾问。 “首先，该设备去除患者功能失调的白蛋白，并将新鲜的白蛋白注入患者体内。其次，它吸附循环内毒素，导致全身炎症显着减弱，并直接影响其他器官衰竭的恢复。”

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In the News

AUGUST 13, 2021
New Dialysis Machine May Reverse Liver Failure
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Banwari Agarwal, MBBS, MD

Hope may be on the horizon for people who have acute-on-chronic liver failure, according to results from an early-phase international, multicenter study.

Researchers have found that DIALIVE, a novel liver dialysis device, is safe and effective in this group of patients, significantly increasing the proportion of them who recover from organ failure and shortening the time required to do so.

“DIALIVE is a mechanical liver device, which hits at the heart of what we believe are the two most important pathobiological mechanisms which drive further organ failure in patients with acute-on-chronic liver failure,” said Banwari Agarwal, MBBS, MD, a consultant in critical care medicine at the Royal Free Hospital in London. “First, the device removes a patient’s dysfunctional albumin and infuses fresh albumin into the patient. Second, it adsorbs circulating endotoxin, which leads to a significant attenuation of systemic inflammation and has a direct impact on recovery of other organ failure.”

https://www.gastroendonews.com/I ... mp;utm_medium=title