他汀类药物有望抑制肝病进展

StephenW

他汀类药物有望抑制肝病进展
Prashanth Francis M.D., Ph.D., Lisa M. Forman M.D., M.S.C.E.
首次发布：2021 年 12 月 20 日
https://doi.org/10.1002/cld.1143

潜在利益冲突：无需报告。
他汀类药物（一类降胆固醇药物）的心血管和死亡率益处代表了 20 世纪的重大医学突破之一。 对其强大益处的进一步研究导致发现了新的分子机制以及心血管疾病以外的有益临床效果。 我们之前回顾了他汀类药物在慢性肝病中的安全性，1 现在我们回顾了越来越多的科学和临床证据，这些证据表明他汀类药物对肝病进展有益。
Statins Show Promise Against Progression of Liver Disease
Prashanth Francis M.D., Ph.D., Lisa M. Forman M.D., M.S.C.E.
First published: 20 December 2021
https://doi.org/10.1002/cld.1143

Potential conflict of interest: Nothing to report.
The cardiovascular and mortality benefit of statins, a class of cholesterol-lowering medications, represents one of the major medical breakthroughs of the 20th century. Further research into their robust benefits led to the discovery of novel molecular mechanisms and also beneficial clinical effects beyond cardiovascular disease. We previously reviewed the safety of statin use in chronic liver disease,1 and here we review the growing scientific and clinical evidence suggesting benefit for statin use against the progression of liver disease.

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