肝血管瘤自發消退：46例單機構分析

StephenW

肝血管瘤自發消退：46例單機構分析

Aydin, Oğuzhan a; Acunaş, Bülent b; Poyanli, Arzu b; Rahmi Serin, Kürşat a;伊比什，切馬；厄茲登，伊爾金
作者信息
歐洲胃腸病學和肝病學雜誌：2021 年 11 月 - 第 33 卷 - 第 11 期 - 第 1436-1440 頁
doi：10.1097/MEG.0000000000002069

  
普通外科（肝胰膽外科）

b 放射學，伊斯坦布爾醫學院，伊斯坦布爾大學，伊斯坦布爾，土耳其

2020 年 8 月 27 日接收 2020 年 11 月 18 日接受

致信 Oğuzhan Aydin, MD, 伊斯坦布爾醫學院，Millet Caddesi-Çapa-Şehremini，伊斯坦布爾大學，伊斯坦布爾 34390，土耳其，電話/傳真：+90 (212) 635 30 82；電子郵箱：[email protected]


抽象的
客觀的

本研究的目的是確定肝血管瘤自發消退的性質。
患者和方法

評估了1988年至2018年期間就診的肝血管瘤患者的記錄。對 716 名接受橫斷面成像隨訪至少 3 年的成年患者的數據進行了分析。
結果

46 名患者 (6.4%) 記錄到自發消退。 28 名患者 (61%) 有單個血管瘤，8 名 (17%) 有兩個血管瘤；其他 10 名患者有 3-6 個血管瘤。在 46 名患者的 87 處病變中，69 處實際上在研究期間消退。 12 名多處病變的患者表現出不一致的病程——多處病變患者的血管瘤之一消退，而另一名擴大或保持穩定。 11 個退化的血管瘤首先表現出擴大，然後是自然消退。 14 個（20%）退化的血管瘤獲得了非典型特徵，如果原始電影不可用，這些特徵將表明惡性腫瘤。
結論

肝血管瘤的自發消退是一種未被充分認識的現象。擴大不應該是乾預的直接指示，因為它可能伴隨著退化。在對可疑惡性腫瘤的肝髒病變進行鑑別診斷時，應考慮退化性血管瘤。
版權所有 © 2021 Wolters Kluwer Health, Inc.。保留所有權利。

StephenW

Spontaneous regression of liver hemangiomas: a single-institution analysis of 46 patients

Aydin, Oğuzhan a; Acunaş, Bülent b; Poyanli, Arzu b; Rahmi Serin, Kürşat a; İbiş, Cema; Özden, İlgin a
Author Information
European Journal of Gastroenterology & Hepatology: November 2021 - Volume 33 - Issue 11 - p 1436-1440
doi: 10.1097/MEG.0000000000002069

  
Departments of a General Surgery (Hepatopancreatobiliary Surgery Unit)

b Radiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

Received 27 August 2020 Accepted 18 November 2020

Correspondence to Oğuzhan Aydin, MD, İstanbul Faculty of Medicine, Millet Caddesi-Çapa-Şehremini, Istanbul University, İstanbul 34390, Turkey, Tel/fax: +90 (212) 635 30 82; e-mail: [email protected]


Abstract
Objective

The aim of this study was to determine the nature of spontaneous regression of liver hemangiomas.
Patients and methods

The records of the liver hemangioma patients who attended the outpatient  clinic between 1988 and 2018 were evaluated. The data of the 716 adult patients who were followed for at least 3 years with cross-sectional imaging were analyzed.
Results

Spontaneous regression was documented in 46 patients (6.4%). Twenty-eight patients had a single hemangioma (61%), eight (17%) had two hemangiomas; the other 10 patients had 3–6 hemangiomas. Of the 87 lesions in 46 patients, 69 actually regressed during the study. Twelve patients with more than one lesion exhibited discordant courses – one of the hemangiomas of a patient with multiple lesions regressed, whereas the other enlarged or remained stable. Eleven of the regressed hemangiomas exhibited enlargement first, followed by spontaneous regression. Fourteen (20%) of the regressed hemangiomas acquired atypical characteristics that would have suggested a malignancy had the original films been unavailable.
Conclusion

Spontaneous regression of liver hemangiomas is an underrecognized phenomenon. Enlargement should not be a straightforward indication for intervention because it may be followed by regression. A regressed hemangioma should be considered in the differential diagnosis of liver lesions suspicious for malignancy.
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.