家庭成员中乙型肝炎病毒感染的患病率和相关因素：北京的

StephenW

Prevalence and factors associated with hepatitis B virus infection among household members: a cross-sectional study in Beijing
Xuan Zhao  1 , Xuefeng Shi  2 , Min Lv  3 , Beibei Yuan  1 , Jian Wu  3
Affiliations
Affiliations

    1
    China Center for Health Development Studies, Peking University , Beijing, China.
    2
    School of Management, Beijing University of Chinese Medicine , Beijing, China.
    3
    Beijing Center for Disease Control and Prevention, Beijing Research Center for Preventive Medicine , Beijing, China.

    PMID: 33606606 DOI: 10.1080/21645515.2020.1847951

Abstract

HBV prevention and control presents a global public health priority because of the tremendous economic and healthcare burdens involved. This study was designed to investigate the status of HBV epidemics among household members, and to analyze the risk factors of HBV infection in couples and their offspring. A total of 1,035 couples and 541 offspring were included. We sourced the data from a population-based serological survey conducted by the Beijing Center for Disease Prevention and Control in 2014. Chi-square test and multiple logistic were used to assess differences in the prevalence of categorical variables, and identify risk factors for HBV infection and exposure in couples and offspring after controlling for confounding factors. In couples, the prevalence of chronic HBV infection was 4.3% and the prevalence of exposure 32.7%. The prevalence of chronic HBV infection in offspring was 0.9%, and the prevalence of exposure 8.7%. Sharing syringes with others and living with a spouse who was infected or exposed to HBV were associated with a significantly higher risk for transmission of HBV for couples. In offspring, maternal HBV infection was a significant risk factor for HBV exposure. This study provides evidence that having household members infected or exposed to HBV increases the risk of HBV transmission, and in order to achieve better control of HBV infection effective strategies must be established to prevent intra-familial transmission.

Keywords: Cross-sectional; familial transmission; hepatitis B virus; household members.

StephenW

家庭成员中乙型肝炎病毒感染的患病率和相关因素：北京的一项横断面研究
宣照1，学风师2，闵吕3，北be园1，建武3
隶属关系
隶属关系

    1个
    北京大学中国卫生发展研究中心，北京，中国。
    2
    北京中医药大学管理学院，北京
    3
    北京市疾病预防控制中心，北京预防医学研究中心，北京，中国。

    PMID：33606606 DOI：10.1080 / 21645515.2020.1847951

抽象的

由于涉及巨大的经济和医疗负担，HBV预防和控制成为全球公共卫生的重点。本研究旨在调查家庭成员中HBV流行状况，并分析夫妻及其后代中HBV感染的危险因素。一共包括1,035对夫妇和541个后代。我们从北京疾病预防控制中心于2014年进行的基于人群的血清学调查中获得了数据。卡方检验和多元Logistic检验用于评估分类变量的流行率差异，并确定HBV感染的危险因素控制混杂因素后，对夫妇和后代的接触和暴露。在夫妇中，慢性HBV感染的患病率为4.3％，暴露的患病率为32.7％。子代慢性HBV感染的患病率为0.9％，暴露的患病率为8.7％。与他人共用注射器并与被感染或暴露于HBV的配偶同住会大大增加夫妇传播HBV的风险。在后代中，孕妇的HBV感染是HBV暴露的重要危险因素。这项研究提供的证据表明，家庭成员感染或暴露于HBV会增加HBV传播的风险，为了更好地控制HBV感染，必须制定有效的策略来防止家庭内传播。

关键字：横截面；家族传播；乙型肝炎病毒;家庭成员。

StephenW

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