中性粒细胞计数与白蛋白比率可作为HBV相关性失代偿性肝硬

StephenW

Neutrophil count to albumin ratio as a prognostic indicator for HBV-associated decompensated cirrhosis
Zhong Han  1 , Xia He  1 , SongQing Peng  1
Affiliations
Affiliation

    1
    Department of Clinical Laboratory, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, China.

    PMID: 33609049 DOI: 10.1002/jcla.23730

Abstract

Background: To explore the value of neutrophil count to albumin ratio (NAR) in predicting the outcomes of patients with HBV-associated decompensated cirrhosis (HBV-DeCi).

Methods: One hundred and fifty-four HBV-DeCi patients were enrolled. The 30-day mortality was determined. Multivariate analysis was applied to identify risk factors for poor outcomes. Receiver operating characteristic curve analyses was performed to evaluate prognostic accuracy.

Results: The 30-day mortality was 10.4%. NAR was significantly higher in non-survivors than in survivors and was an independent predictor for unfavorable prognosis.

Conclusions: The present results indicate that increased NAR is associated with poor survival in HBV-DeCi patients and has potential for clinical application.

Keywords: decompensated cirrhosis; hepatitis B virus; mortality; neutrophil count to albumin ratio; prognostic factor.

© 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC.

StephenW

中性粒细胞计数与白蛋白比率可作为HBV相关性失代偿性肝硬化的预后指标
钟汉1，夏河1，宋庆鹏1
隶属关系
联系

    1个
    浙江大学附属第一医院Sheng州分院Sheng州人民医院检验科，中国Sheng州市。

    PMID：33609049 DOI：10.1002 / jcla.23730

抽象的

背景：探讨嗜中性粒细胞计数与白蛋白比率（NAR）在预测HBV相关性失代偿性肝硬化（HBV-DeCi）患者预后中的价值。

方法：纳入154例HBV-DeCi患者。确定30天的死亡率。应用多变量分析确定不良预后的危险因素。进行受试者工作特征曲线分析以评估预后准确性。

结果：30天死亡率为10.4％。非存活者中的NAR显着高于存活者，并且是不良预后的独立预测因子。

结论：目前的结果表明，NAR升高与HBV-DeCi患者的不良生存有关，并具有临床应用潜力。

关键词：失代偿性肝硬化；乙型肝炎病毒;死亡;中性粒细胞计数与白蛋白比率；预后因素。

©2021作者。由Wiley Periodicals LLC发布的《临床实验室分析杂志》。

StephenW

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcla.23730