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肝胆相照论坛 论坛 学术讨论& HBV English 平均血小板体积/淋巴细胞比作为HBV相关代偿性肝硬化的预 ...
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平均血小板体积/淋巴细胞比作为HBV相关代偿性肝硬化的预后 [复制链接]

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发表于 2020-7-27 20:00 |只看该作者 |倒序浏览 |打印
Mean Platelet Volume/Lymphocyte Ratio as a Prognostic Indicator for HBV-Related Decompensated Cirrhosis
JianPing Wu  1 , WeiLin Mao  1 , XinKe Li  2
Affiliations
Affiliations

    1
    Department of Clinical Laboratory, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China.
    2
    Department of Radiation Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003 Zhejiang, China.

    PMID: 32714387 PMCID: PMC7352138 DOI: 10.1155/2020/4107219

Abstract

Aim: To evaluate the prognostic role of the mean platelet volume/lymphocyte ratio (MPVLR) for mortality in patients with hepatitis B virus-related decompensated cirrhosis (HBV-DeCi).

Methods: The medical records of 101 patients with HBV-DeCi were retrospectively reviewed, and their baseline clinical and laboratory characteristics were extracted. The predictive value of the MPVLR for death was estimated using receiver operating characteristic curve analysis and a multivariate logistic regression model.

Results: Patients with HBV-DeCi in the high-MPVLR group exhibited significantly increased 90-day mortality compared with that of the patients within the low-MPVLR group, and MPVLR was an independent predictor of 90-day mortality in patients with HBV-DeCi.

Conclusions: Increased MPVLR is associated with poor outcomes in patients with HBV-DeCi and might be a useful component of future prognostic scores.

Copyright © 2020 JianPing Wu et al.

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发表于 2020-7-27 20:00 |只看该作者
平均血小板体积/淋巴细胞比作为HBV相关代偿性肝硬化的预后指标
吴建平1,魏林茂1,李新科2
隶属关系
隶属关系

    1个
    浙江大学医学院附属第一医院临床检验科,浙江杭州310003
    2
    浙江大学医学院附属第一医院放疗科,浙江杭州310003

    PMID:32714387 PMCID:PMC7352138 DOI:10.1155 / 2020/4107219

抽象

目的:评估平均血小板体积/淋巴细胞比(MPVLR)对乙型肝炎病毒相关代偿性肝硬化(HBV-DeCi)患者死亡率的预后作用。

方法:回顾性分析101例HBV-DeCi患者的病历,并提取其基线临床和实验室特征。使用接收者工作特征曲线分析和多元逻辑回归模型估算MPVLR死亡的预测价值。

结果:与低MPVLR组相比,高MPVLR组的HBV-DeCi患者的90天死亡率显着增加,而MPVLR是HBV-DeCi患者90天死亡率的独立预测因子。

结论:MPVLR升高与HBV-DeCi患者预后不良有关,可能是未来预后评分的有用组成部分。

版权所有©2020 JianPing Wu等。
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