乙型肝炎的治愈：模拟潜在治愈成本的经济性。

StephenW

Curr Opin HIV AIDS. 2020 Mar 23. doi: 10.1097/COH.0000000000000617. [Epub ahead of print]
Hepatitis B cure: modeling the economics of a potential cost of a cure.
Toy M1, So S1, Hutton DW2.
Author information

1
    Department of Surgery, Asian Liver Center, Stanford University School of Medicine, Palo Alto, California.
2
    Department of Health Management and Policy, University of Michigan, Ann Arbor, Michigan, USA.

Abstract
PURPOSE OF REVIEW:

The cure for hepatitis C virus infection has raised hope for a potential hepatitis B virus (HBV) cure, but the high price tag has led to serious questions about the affordability, and thus to access for all. This review discusses cost-effectiveness models, affordability, and access to a potential new cure for chronic HBV infection.
RECENT FINDINGS:

A cure does not yet exist for HBV, but the antiviral treatments that are currently available help slow down the progression of disease. There is limited research in the area of cost-effectiveness and economic analysis comparing a potential cure. Our preliminary findings from modeling and economic threshold analysis show that cure could be potentially cost-effective or cost-saving. Governments can possibly use the results of economic models for price negotiations.
SUMMARY:

The highest burden of the HBV infection is in low and middle-income countries. Given that the cost of current treatment has dropped dramatically in recent years as the first line treatments have come off patent, the price for a HBV cure needs to be reasonable and affordable to all people.

PMID:
    32209813
DOI:
    10.1097/COH.0000000000000617

StephenW

Curr Opin HIV艾滋病。 2020年3月23日。doi：10.1097 / COH.0000000000000617。 [Epub提前发行]
乙型肝炎的治愈：模拟潜在治愈成本的经济性。
玩具M1，所以S1，哈顿DW2。
作者信息

1个
    斯坦福大学医学院亚洲肝脏中心手术科，加利福尼亚帕洛阿尔托。
2
    密歇根大学健康管理与政策系，美国密歇根州安阿伯。

抽象
审查目的：

丙型肝炎病毒感染的治愈方法为潜在的乙型肝炎病毒（HBV）治愈方法带来了希望，但高昂的价格已引起人们对可负担性的严重质疑，因此所有人都可以使用。这篇综述讨论了成本效益模型，可负担性以及获得潜在治疗慢性HBV感染的新方法。
最近发现：

HBV尚无治愈方法，但是目前可用的抗病毒治疗有助于减缓疾病的进展。在成本效益和经济分析方面，比较可能的治疗方法的研究有限。我们从建模和经济阈值分析中获得的初步结果表明，固化可能具有成本效益或节省成本的潜力。政府可以将经济模型的结果用于价格谈判。
摘要：

乙肝病毒感染的最大负担是在中低收入国家。鉴于近年来的治疗费用已随着一线治疗专利的使用而急剧下降，因此HBV治疗的价格必须合理且所有人都可以负担。

PMID：
    32209813
DOI：
    10.1097 / COH.0000000000000617