持续用ABI-H0731 + NrtI进行治疗可导致HBeAg阳性患者的HBV DNA，HBV

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Continued Therapy with ABI-H0731 + NrtI Results in Sequential Reduction/Loss of HBV DNA, HBV RNA, HBeAg, HBcrAg and HBsAg in HBeAg-Positive Patients                                                                         AASLD 2019 Nov 8-12 Boston Reported by Jules Levin Mark S. Sulkowski1, Kosh Agarwal2, Scott Fung3, Man-Fung Yuen4, Xiaoli Ma5, Jacob Lalezari6, Tuan T. Nguyen7, Ho Bae8, Eugene R. Schiff9, Tarek Hassanein10, Hie-Won Hann11, Magdy Elkhashab12, Douglas Dieterich13, Paul Kwo14, Ronald Nahass15, Alnoor Ramji16,James Park17, Natarajan Ravendhran18, Sing Chan19, Frank Weilert20, Steven-Huy Han21, Walid Ayoub22, Edward Gane23, Ira Jacobson17, Michael Bennett24, Maurizio Bonacini6, Hany Zayed25, Katia Alves25, Qi Huang25, Eric Ruby25, Dongmei Qiang25, Steven J. Knox25 and Richard Colonno25 1Johns Hopkins University School of Medicine, Baltimore, MD; 2Institute of Liver Studies, King's College Hospital, London, UK; 3University of Toronto, Toronto, ON, Canada; 4University of Hong Kong, Hong Kong; 5Office of Xiaoli Ma, Philadelphia, PA; 6Quest Clinical Research, San Francisco, CA; 7T. Nguyen Research and Education, San Diego, CA; 8Asian Pacific Liver Center, Los Angeles, CA; 9Schiff Center for Liver Diseases, Miami, FL; 10Southern California Research Center, Coronado, CA; 11Thomas Jefferson University Hospital, Philadelphia, PA; 12Toronto Liver Center, Toronto, ON, Canada; 13Icahn School of Medicine at Mount Sinai, New York, NY; 14Stanford University Medical Center, Stanford, CA; 15Infectious Disease Care, Hillsborough, NJ; 16Providence Health Care Research Institute, Vancouver, BC, Canada; 17New York University Langone Medical Center, New York, NY; 18Digestive Disease Associates, Catonsville, MD; 19Sing Chan, MD, Flushing, New York, NY; 20Waikato Hospital, Hamilton, New Zealand; 21Pfleger Liver Institute at University of California Los Angeles, CA; 22Cedars-Sinai Medical Center, Los Angeles, CA; 23Auckland Clinical Studies Limited, Auckland, New Zealand; 24Medical Associates Research Group, San Diego, CA; and 25Assembly Biosciences, Inc., South San Francisco, CA

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