肝靶向抑制PAPD5和PAPD7导致 AAV-HBV小鼠模型中可持续的HBsAg降低

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LIVER-TARGETED INHIBITION OF PAPD5 AND PAPD7 LEADS TO SUSTAINABLE HBsAg REDUCTION IN THE AAV-HBV MOUSE MODEL                                                                          AASLD 2019 Nov 8-12 Boston Reported by Jules Levin XueZhou2, YoujunYu2, AnaïsLopez1, Josephine Felber1, Helene Gylling3, Gitte Friis3, LykkePedersen3, SørenOttosen3, Anna-Maria Geretti1and Henrik Mueller1 1Roche Innovation Center Basel, Basel, Switzerland; 2. Roche Innovation Center Shanghai, Shanghai, China; 3. Roche Innovation Center Copenhagen, Hørsholm, Denmark