慢性乙型肝炎人口老龄化伴随着合并症的增加 - 2000年至2017

StephenW

An aging population of chronic hepatitis B with increasing co-morbidities – A territory-wide study from 2000 to 2017

Hepatology — Wong GLH, et al. | June 28, 2019

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In this investigation involving 135,395 chronic hepatitis B (CHB) patients, researchers determined the prevalence of key co-morbidities and concomitant medications in a territory-wide CHB cohort in Hong Kong in 2000-2017. The demographics and prevalence of key co-morbidities, including diabetes mellitus, hypertension, chronic kidney disease, osteopenia/osteoporosis based on diagnosis codes, relevant medications and/or laboratory parameters were determined in 4 time periods according to the first appearance of CHB patients: 2000-2004, 2005-2009, 2010-2013 and 2014-2017. Data reported that there has been a trend of increasing prevalence of several common co-morbidities over the 4 periods: hypertension 25.5%, 23.8%, 27.2% and 28.6%; diabetes mellitus 10.6%, 12.5%, 16.1% and 20.1%; cardiovascular disease 12.5%, 16.9%, 20.9% and 22.2%, and malignancy 7.0%, 13.2%, 17.3% and 23.6%, respectively. With the increasing prevalence of common co-morbidities, CHB patients are getting older. When selecting antiviral therapy, these co-morbidities should be taken into consideration.

StephenW

慢性乙型肝炎人口老龄化伴随着合并症的增加 -  2000年至2017年的全国性研究

肝脏病学 -  Wong GLH，et al。 | 2019年6月28日

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在涉及135,395名慢性乙型肝炎（CHB）患者的调查中，研究人员确定了2000  -  2017年香港全港CHB队列中关键合并症和伴随药物的流行情况。根据CHB患者的首次出现，在4个时间段内确定关键合并症的人口统计学和流行率，包括糖尿病，高血压，慢性肾病，基于诊断代码的骨质减少/骨质疏松症，相关药物和/或实验室参数： 2000-2004,2005-2009,2010-2013和2014-2017。数据显示，在4个时期内，几种常见合并症的患病率呈上升趋势：高血压分别为25.5％，23.8％，27.2％和28.6％;糖尿病10.6％，12.5％，16.1％和20.1％;心血管疾病分别为12.5％，16.9％，20.9％和22.2％，恶性肿瘤分别为7.0％，13.2％，17.3％和23.6％。随着常见合并症的日益普遍，CHB患者正在变老。选择抗病毒治疗时，应考虑这些合并症。

StephenW

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