[作为乙型肝炎病毒慢性携带者的孕妇在妊娠期和产后期间肝

StephenW

[Management of liver dysfunction during pregancy and postpartum in pregnant women who are chronic carriers of hepatitis B virus].
[Article in Chinese; Abstract available in Chinese from the publisher]
Chen XY1, Wang XX.
Author information

1
    Department of International Medical, Beijing Youan Hospital, Capital Medical University, BeiJing100069, China.

Abstractin English, Chinese

随着临床上对慢性乙型肝炎病毒携带孕妇母婴阻断的重视，该类人群在妊娠期或产后出现肝功能异常的报道逐渐增多，但何时干预、处理方法等问题尚未形成共识。现回顾近期文献报道，发现慢性乙型肝炎病毒携带孕妇，无论是否采用核苷(酸)类似物(NAs)干预，于妊娠期及产后均有一定比例的肝炎发作、甚至重症化，提示产后并非均能安全停药，需要密切随访。建议根据妊娠周数及丙氨酸氨基转移酶水平分类处理。在妊娠期肝炎发作，采用NAs为主的治疗，产后肝炎发作者可采用NAs或干扰素治疗。有报道采用NAs和干扰素联合治疗可达到更高的治疗目标。.
KEYWORDS:

Abnormal liver function; Antiviral therapy; Hepatitis B virus; Pregnant women who are chronic hepatitis B virus carriers

PMID:
    30818910
DOI:
    10.3760/cma.j.issn.1007-3418.2019.02.003