TLR7激动剂RO7020531在慢性乙型肝炎患者中多次给药后引发免疫

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TLR7 agonist RO7020531 triggers immune activation after multiple doses in chronic hepatitis B patients Reported by Jules Levin AASLD 2018 Nov 9-13 SF Edward J. Gane1, KoshAgarwal2, Rosalina Balabanska3, YonghongZhu4, Lu Gao4, Joseph F. Grippo5 , YuyanJin4, Miriam Triyatni6, Ilia Folitar7, RuchiUpmanyu8, Katerina Glavini6, EoinCoakley9, Tomas Racek6, Man-Fung Yuen10 1. Auckland Clinical Studies; 2. Institute of Liver Studies, Kings College Hospital, London; 3. AcibademCity Clinic, TokudaHospital, Sofia; 4. Roche Innovation Center Shanghai 5. Roche Innovation Center New York; 6. Roche Innovation Center Basel; 7. Roche Innovation Center Basel (former employee); 8. Roche Products Ltd;  9. Roche Innovation Center New York (former employee); 10. Queen Mary Hospital, Hong Kong

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