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肝硬化患者门静脉高压的评估:肝静脉压力梯度及以上 [复制链接]

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才高八斗

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发表于 2019-2-9 07:33 |只看该作者 |倒序浏览 |打印
Evaluation of portal hypertension in the cirrhotic patient: hepatic vein pressure gradient and beyond
D. S. Karagiannakis ORCID Icon, T. Voulgaris ORCID Icon, S. I. Siakavellas ORCID Icon, G. V. Papatheodoridis ORCID Icon & J. Vlachogiannakos ORCID Icon
Pages 1153-1164 | Received 08 Apr 2018, Accepted 21 Jul 2018, Published online: 21 Oct 2018

    Download citation https://doi.org/10.1080/00365521.2018.1506046



Abstract

Portal hypertension (PH) is a major complication of liver cirrhosis, as it predisposes to the development of serious clinical manifestations such as ascites, hepatic encephalopathy and variceal bleeding. Till now, the measurement of hepatic vein pressure gradient (HVPG) is the gold standard method to ascertain the presence and significance of PH, as many studies have shown its correlation with the appearance of varices and the possibility of variceal bleeding. However, the invasiveness of this procedure makes it difficult to be used in daily clinical practice. Several noninvasive methods with adequate capability of evaluating liver fibrosis, including elastographic techniques, are currently used as alternatives to HVPG in order to assess the presence and the severity of PH. The aim of this paper is to express an overview of the literature about the actual role of HVPG and all available noninvasive tests on the prediction of development of PH complications, to highlight their advantages and their potential limitations, and to provide the latest trends on clinical practice.
Keywords: Cirrhosis, portal hypertension, variceal bleeding, liver stiffness, spleen stiffness

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才高八斗

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发表于 2019-2-9 07:33 |只看该作者
肝硬化患者门静脉高压的评估:肝静脉压力梯度及以上
D. S. Karagiannakis ORCID Icon,T。Voulgaris ORCID Icon,S。I. Siakavellas ORCID Icon,G。V. Papatheodoridis ORCID Icon&J。Vlachogiannakos ORCID Icon
第1153-1164页| 2018年4月8日收到,2018年7月21日接受,2018年10月21日在线发布

    下载引文https://doi.org/10.1080/00365521.2018.1506046



抽象

门静脉高压症(PH)是肝硬化的主要并发症,因为它易于发生严重的临床表现,如腹水,肝性脑病和静脉曲张出血。到目前为止,肝静脉压力梯度(HVPG)的测量是确定PH的存在和显着性的金标准方法,因为许多研究表明它与静脉曲张的出现和静脉曲张出血的可能性相关。然而,该方法的侵入性使其难以用于日常临床实践中。目前,一些具有足够评估肝纤维化能力的非侵入性方法(包括弹性成像技术)被用作HVPG的替代品,以评估PH的存在和严重程度。本文的目的是表达关于HVPG的实际作用和所有可用的非侵入性试验的文献的概述,以预测PH并发症的发展,突出它们的优势和潜在的局限性,并提供临床的最新趋势实践。
关键词:肝硬化,门静脉高压症,静脉曲张出血,肝硬度,脾僵硬

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发表于 2019-2-9 22:18 |只看该作者
回复 StephenW 的帖子

挺重要的问题,顶!

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4
发表于 2019-3-15 05:10 |只看该作者
不知道未来攻克乙肝了,肝硬化这群人会怎样样
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