隐匿性乙型肝炎病毒感染的生物学和临床影响的最新进展

StephenW

Update on Biology and Clinical Impact of Occult Hepatitis B Virus Infection

CME

In the last years, the knowledge on occult HBV infection has greatly increased. Some important virological and immunonological aspects have been clarified. The molecular basis of occult HBV infection has been identified as the long-lasting persistence of HBV cccDNA in the form of a transcriptionally suppressed minichromosome. In addition, there is growing evidence supporting its clinical impact in different clinical scenarios. In fact, apart from the well-established risks of acute and often fatal reactivation in the course of immune-suppressive therapy and of HBV transmission in cases of liver transplantation and blood transfusion, occult HBV infection might be a factor that negatively influences the outcome of the disease if other causes of liver damage (HCV infection, ASH, NASH, hemochromatosis, etc.), co-exist. The meeting will be a unique occasion to discuss both the different aspects of this important and particular phase of the HBV infection and new strategies for a complete-or at least functional-HBV cure.

Venue: Palazzo dei Congressi
Date

October 1-2, 2018
Location

Taormina, Italy
Email

[email protected]
Website

spaziocongressi.it/obi-meeting-2018

StephenW

隐匿性乙型肝炎病毒感染的生物学和临床影响的最新进展

CME

在过去几年中，隐匿性HBV感染的知识大大增加。一些重要的病毒学和免疫学方面已得到澄清。隐匿性HBV感染的分子基础已被确定为HBV cccDNA以转录抑制的微染色体形式持久存在。此外，越来越多的证据支持其在不同临床情况下的临床影响。事实上，除了在免疫抑制治疗过程中急性和通常致命的再激活以及肝移植和输血的HBV传播的明确风险之外，隐匿性HBV感染可能是对其结果产生负面影响的因素。如果其他原因导致肝脏损害（HCV感染，ASH，NASH，血色病等）并存。会议将是一个独特的场合，讨论HBV感染这一重要和特定阶段的不同方面以及完全或至少功能性HBV治愈的新策略。

地点：Palazzo dei Congressi
日期

2018年10月1日至2日
位置

陶尔米纳，意大利
电子邮件

[email protected]
网站

spaziocongressi.it/obi-meeting-2018