超声评估肝纤维化

StephenW

J Med Ultrasound. 2017 Jul-Sep;25(3):127-129. doi: 10.1016/j.jmu.2017.04.001. Epub 2017 Jun 7.
Ultrasound Evaluation of Liver Fibrosis.
Lin YS1,2,3,4.
Author information

1
    Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
2
    Division of Gastroenterology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei Campus, Taiwan.
3
    MacKay Medical College, New Taipei City, Taiwan.
4
    MacKay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan.

Abstract

Early diagnosis of liver fibrosis is an important factor affecting the efficacy of chronic hepatitis treatment. In the past, the diagnosis of liver fibrosis was dependent on a liver biopsy which has several shortcomings as sampling error, intra- or inter-observation variations and possible procedure-related complications. Ultrasound-based elastography, tissue elastography (TE) and acoustic radiation force impulse (ARFI) have been developed to assess liver fibrosis. Current clinical evidence indicates that TE and ARFI had high sensitivities and specificities to diagnosis from significant fibrosis to liver cirrhosis. TE and ARFI can not only assess liver fibrosis but can also be used to predict prognosis. In practical, ARFI can also be used on a regular basis to evaluate the degree of liver fibrosis for chronic hepatitis B and C, nonalcoholic fatty liver disease, and alcoholic liver disease.
KEYWORDS:

ARFI; acoustic radiation force impulse; liver biopsy; tissue elastography

PMID:
    30065476
PMCID:
    PMC6029306
DOI:
    10.1016/j.jmu.2017.04.001

StephenW

J Med超声波。 2017年7月至9月; 25（3）：127-129。 doi：10.1016 / j.jmu.2017.04.001。 Epub 2017年6月7日。
超声评估肝纤维化。
林YS1,2,3,4。
作者信息

1
    台北医科大学医学院临床医学研究所，台湾台北。
2
    台湾台北校区麦凯纪念医院内科，消化内科。
3
    台湾新北市麦凯医学院。
4
    台湾台北市麦凯医学院护理与管理专科学校。

抽象

肝纤维化的早期诊断是影响慢性肝炎治疗效果的重要因素。过去，肝纤维化的诊断依赖于肝活检，其具有取样误差，观察内或观察间变化以及可能的手术相关并发症等几个缺点。已经开发了基于超声的弹性成像，组织弹性成像（TE）和声辐射力脉冲（ARFI）来评估肝纤维化。目前的临床证据表明，TE和ARFI对从显着纤维化到肝硬化的诊断具有高度敏感性和特异性。 TE和ARFI不仅可以评估肝纤维化，还可以用于预测预后。实际上，ARFI也可以定期用于评估慢性乙型和丙型肝炎，非酒精性脂肪性肝病和酒精性肝病的肝纤维化程度。
关键词：

ARFI;声辐射力脉冲;肝活检;组织弹性成像

结论：
    30065476
PMCID：
    PMC6029306
DOI：
    10.1016 / j.jmu.2017.04.001