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Zhonghua Zhong Liu Za Zhi. 2018 Jul 23;40(7):481-489. doi: 10.3760/cma.j.issn.0253-3766.2018.07.001.
[Primary prevention model of liver cancer in rural China].
[Article in Chinese; Abstract available in Chinese from the publisher]
Qu CF1, Chen TY2, Wang YT1, Yao HY2, Chen K1, Zhu J2, Chen WQ3, He H1.
Author information
1
State Key Laboratory of Molecular Oncology/Department of Immunology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
2
Qidong People's Hospital & Qidong Liver Cancer Institute, Qidong 226200, China.
3
Office for Cancer Sceening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Abstractin English, Chinese
原发性肝癌的主要病理类型是肝细胞癌(HCC),其病因相对清楚,慢性乙肝病毒感染是我国高发区HCC的主要病因,其次为黄曲霉毒素暴露。在江苏省启东市开展的肝癌一级预防干预措施中,新生儿期接种乙肝疫苗对<30岁人群肝癌发病的保护率为84% (95% CI为23%~97%);清洁饮水和降低黄曲霉毒素暴露后,<35岁人群的肝癌发病风险与30年前比较,降低至少4倍。清洁水源、防霉改粮、预防乙型肝炎病毒感染是农村高发区有效的肝癌一级预防模式。.
KEYWORDS:
Liver neoplasms; Population-based Study; Primary Prevention
PMID:
30060354 |
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