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Management of chronic hepatitis B during pregnancy
Aysha Aslam Karen Joanie Campoverde Reyes Vijayram Reddy Malladi Rizwan Ishtiaq Daryl T Y Lau
Gastroenterology Report, goy025, https://doi.org/10.1093/gastro/goy025
Published:
24 July 2018
Abstract
Chronic hepatitis B is globally prevalent and is a major cause of cirrhosis and hepatocellular carcinoma. Despite immunoprophylaxis against hepatitis B in pregnancy, perinatal transmission still occurs in at least 10% of the children born to a mother with high level of viremia. Decisions regarding hepatitis B therapy during pregnancy must take into account the benefits and safety for both the mother and the unborn baby. In this review, we summarize the current treatment options for chronic hepatitis B with a focus on management during pregnancy and the evidence-based strategies to prevent vertical transmission of hepatitis B virus (HBV).
Chronic hepatitis B, pregnancy, nucleoside analogue, hepatitis B therapy
Topic:
pregnancy hepatitis b hepatitis b, chronic mothers hepatitis b virus maternal transmission
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