HBsAg阳性孕妇

StephenW

Clin Exp Obstet Gynecol. 2016;43(6):866-870.
Monitoring and treatment results of 88 HBsAg-positive pregnant women.
Kolgelier S, Sumer S, Demir NA, Asci Z, Demir LS, Ozcimen S, Ural O.
Abstract

Approximately 5% of all women in the world are HBsAg-positive. Chronic hepatitis B is a problem in women of reproductive age. This paper assessed 88 HBsAg-positive pregnant women, of whom 11 began treatment during pregnancy and five became pregnant while receiving treatment. The files of HBsAg-positive pregnant women were reviewed between January 2010 and December 2013-retrospectively. From these 88 pregnant women, 72 did not receive any treatment during their pregnancy, 11 began treatment during their pregnancy, and five became pregnant while receiving treatment. Nine of these 11 pregnant women were given tenofovir disoproxil fumarate and two of them lamivudine. Ten babies of the 11 mothers that began treatment during their pregnancy were healthy, but one was lost due to preterm birth. Of the five patients who became pregnant while receiving treatment, the treatments of four women were discontinued and they were monitored during their pregnancies because mild-moderate (less than stage 3) fibrosis was found in their liver biopsy results. It is important to screen all pregnant women for hepatitis B and to assess those found HBsAg-positive. It is possible to protect both the mother and baby using appropriate approaches.

PMID:
    29944240

StephenW

Clin Exp Obstet Gynecol。 2016; 43（6）：866-870。
HBsAg阳性孕妇。
Kolgelier S，Sumer S，Demir NA，Asci Z，Demir LS，Ozcimen S，Ural O.
摘要

世界上约有5％的女性是HBsAg阳性。慢性乙型肝炎是育龄妇女的一个问题。本文评估了88例HBsAg阳性孕妇，其中11例在怀孕期间接受了治疗。回顾性分析2010年1月至2013年12月HBsAg阳性孕妇的文件。从这88名孕妇中，有72名怀孕期间没有接受任何治疗。这11名孕妇中有9名服用了替诺福韦酯，富马酸替诺福韦和两种拉米夫定。在怀孕期间接受治疗的11位母亲中的10位婴儿健康，但其中一位失去了早产。在5名已接受治疗的患者中，他们在妊娠期间接受了治疗，因为在他们的肝活检结果中发现轻度 - 中度（少于3期）纤维化。 HBsAg阳性是其中最重要的一种。使用适当的方法可以保护母亲和婴儿。

结论：
    29944240

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