S0意味着没有纤维化。 S4是肝硬化。 在此之间，S1仅在门区出现轻度纤维化。 S2是门脉区之间的纤维化中度阶段，但没有小叶结构的破坏。 S3是严重的纤维化。 在这个阶段，门脉区域之间以及门脉区域和中心静脉之间存在纤维性桥接。 在S4，除了S3的变化，还形成假小叶，这个阶段是肝硬化的最后阶段。
S0 means no fibrosis. S4 is cirrhosis. In between, S1 is a mild fibrosis only seen at the portal area. S2 is a moderate stage of fibrosis, between portal areas, but without the destruction of the lobular structure. S3 is severe fibrosis. At this stage, there is fibrostic bridging between portal areas and between portal areas and center veins. At S4, in addition to S3's changes, there are pseudo-lobules formed and this stage is the final stage, cirrhosis.