[肝细胞癌：发病率或未来瘟疫的增加？]

StephenW

Bull Cancer. 2018 Mar 19. pii: S0007-4551(18)30076-6. doi: 10.1016/j.bulcan.2018.02.003. [Epub ahead of print]
[Hepatocellular carcinoma: Increase in incidence or future plague?] [Article in French]
Raoul JL1, Raimbourg J2, Hiret S2, Adhoute X3, Senellart H2.
Author information
1Institut de cancérologie de l'Ouest, département d'oncologie médicale, site de Nantes, boulevard J.-Monod, 44805 Saint-Herblain cedex, France. Electronic address: [email protected].2Institut de cancérologie de l'Ouest, département d'oncologie médicale, site de Nantes, boulevard J.-Monod, 44805 Saint-Herblain cedex, France.3Hôpital Saint-Joseph, département d'hépato-gastroentérologie, 26, boulevard de Louvain, 13008 Marseille, France.

AbstractHepatocellular carcinoma is the third most frequent cause of cancer death worldwide, particularly in Asia and Africa. Most cases complicate an underlying liver cirrhosis due to hepatitis B or C chronic virus infection or alcoholic abuse. But, following the current epidemics of obesity and type 2 diabetes, it appears that these diseases, associated in metabolic syndrome, are responsible for non alcoholic fatty liver disease at risk of HCC frequently before the stage of cirrhosis. Recent hypotheses consider that in the near future, cancer deaths due to HCC will overpass in USA those due to breast or colorectal cancers. Governments should develop policies to prevent obesity, type 2 diabetes and the metabolic syndrome as well as fight against alcoholism and hepatitis B and C virus infections.


KEYWORDS: Carcinome hépatocellulaire; Cirrhose; Cirrhosis; Diabetes; Diabète; Epidemiology; Hepatocellular carcinoma; Obesity; Obésité; Épidémiologie

PMID:29567280DOI:10.1016/j.bulcan.2018.02.003

StephenW

癌症。 2018年3月19日，pii：S0007-4551（18）30076-6。 doi：10.1016 / j.bulcan.2018.02.003。 [电子版提前打印]
[肝细胞癌：发病率或未来瘟疫的增加？]
[法文]
Raoul JL1，Raimbourg J2，Hiret S2，Adhoute X3，Senellart H2。
作者信息

1
    Institut decancérologiede l'Ouest，départementd'oncologiemédicale，南特网站，boulevard J.-Monod，44805 Saint-Herblain cedex，法国。电子地址：[email protected]。
2
    Institut decancérologiede l'Ouest，départementd'oncologiemédicale，南特网站，boulevard J.-Monod，44805 Saint-Herblain cedex，法国。
3
    位于法国马赛13008，卢瓦恩大道26号的hépato-gastroentérologie医院圣约瑟医院。

抽象

肝细胞癌是全球癌症死亡的第三位最常见的原因，特别是在亚洲和非洲。大多数病例会由于乙型肝炎或丙型肝炎慢性病毒感染或酒精滥用而使潜在的肝硬化复杂化。但是，继目前流行的肥胖症和2型糖尿病之后，似乎这些与代谢综合征相关的疾病在肝硬化阶段之前经常发生HCC风险的非酒精性脂肪肝疾病。最近的假设认为，在不久的将来，由于HCC的癌症死亡将在美国超过那些由于乳腺癌或结肠直肠癌引起的死亡。各国政府应制定政策，预防肥胖，2型糖尿病和代谢综合征，以及防止酗酒和乙肝和丙肝病毒感染。
关键词：

Carcinomehépatocellulaire; Cirrhose;肝硬化;糖尿病;糖尿病反;流行病学;肝细胞癌;肥胖; Obésité; Épidémiologie

结论：
    29567280
DOI：
    10.1016 / j.bulcan.2018.02.003

antiHBVren

各国政府应制定政策，预防肥胖，2型糖尿病和代谢综合征，以及防止酗酒和乙肝和丙肝病毒感染。
HBV排在第五位