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Hepatology International
November 2017, Volume 11, Issue 6, pp 481-484 | Cite as
Mother-to-infant transmission of hepatitis B virus: challenges and perspectives
Authors
Authors and affiliations
Yi-Fen ShihChun-Jen Liu Email author
Yi-Fen Shih 1
Chun-Jen Liu 234Email author
1. Department of Physical Therapy and Assistive TechnologyNational Yang-Ming UniversityTaipeiTaiwan
2. Department of Internal Medicine and Graduate Institute of Clinical Medicine National Taiwan University College of Medicine Taipei Taii
3.Graduate Institute of Clinical MedicineNational Taiwan University College of Medicine and HospitalTaipeiTaiwan
4. Hepatitis Research Center National Taiwan University College of Medicine and Hospital Taipei Taii
Point of View
First Online: 24 October 2017
131 Downloads
Abstract
Despite the active-active immunoprophylaxis using hepatitis B vaccination with or without hepatitis B immunoglobulin (HBIg), up to 8- Understanding the mechanisms of MTIT is essential for the interruption of HBV transmission. There are three possible routes of transmission: intrauterine transmission, transmission during delivery (intrapartum) and postnatal transmission through close contact or breast milk ( postpartum). Overall, positivity for hepatitis B e antigen (HBeAg) and the high viral load of the mothers are the two most important risk factor related to MTIT of HBV. This article briefly reviews the viral factors related to MTIT of HBV and discusses the issues that warrant further investigation.
Keywords
Hepatitis B virus Transmission Viral factor
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发表于 2017-12-4 19:25