异位性皮炎与乙型肝炎抗原阳性负相关：基于群体的队列研

smilingcloud

https://www.ncbi.nlm.nih.gov/pubmed/28646620

Atopicdermatitis is inversely associated with hepatitis B antigen positivity: apopulation-based cohort study.

Abstract

BACKGROUND:

No clearassociation between hepatitis B virus (HBV) infection and atopic dermatitis(AD) has been established. Some studies have reported that subjects with HBVhad an increased risk of atopy; other studies reported an inverse associationbetween HBV seropositivity and allergic diseases.

OBJECTIVE:

Weevaluated the association between AD and hepatitis B antigen (HBsAg) positivityusing Korean National Health and Nutrition Examination Survey data.

METHODS:

Intotal, 14 776 participants aged >19 years were included in the analysis.Multiple logistic regression analyses were used to evaluate the odds ratio ofHBsAg positivity in association with AD and asthma.

RESULTS:

Theprevalence of HBsAg positivity was lower in individuals with AD than in thosewithout AD (mean [SE], 0.7% [0.4] vs. 3.7% [0.2]; P < 0.001). However, HBsAgpositivity was not significantly associated with asthma (3.7% [0.2] vs. 2.8%[0.8]; P < 0.001). HBsAg positivity decreased the risk of AD significantly(OR = 0.223; 95% CI = 0.069-0.72).

CONCLUSIONS:

Thisstudy demonstrates an inverse association between AD and HBsAg positivity usinga nationwide, population-based, cross-sectional health examination and survey.

smilingcloud

抽象
背景：
乙型肝炎病毒（HBV）感染和特应性皮炎（AD）之间没有明确的关联。一些研究报道，乙型肝炎病人的特应性风险增加;其他研究报道了HBV血清阳性与过敏性疾病之间的逆关联。
目的：
我们使用韩国国家健康和营养检查调查数据评估了AD和乙型肝炎抗原（HBsAg）阳性之间的关联。
方法：
共有14 776名年龄> 19岁的参与者被纳入分析。使用多重逻辑回归分析来评估与AD和哮喘相关的HBsAg阳性的优势比。
结果：
AD患者的HBsAg阳性患病率低于无AD患者（平均[SE]，0.7％[0.4] vs. 3.7％[0.2]，P <0.001）。然而，HBsAg阳性与哮喘没有显着相关（3.7％[0.2] vs. 2.8％[0.8]; P <0.001）。 HBsAg阳性明显降低AD的风险（OR = 0.223; 95％CI = 0.069-0.72）。
结论：
本研究使用全国性，基于人群的横断面健康检查和调查显示了AD与HBsAg阳性的逆关联。

smilingcloud

HBs阳性可以降低异位性皮炎的风险。  
这对战友来说，也算是一种心里安慰吧。
HBs阳性 也有正能量的时候。



http://baike.baidu.com/item/%E5% ... E%E8%82%A4%E7%82%8E
异位性皮肤炎
异位性皮肤炎（Atopic dermatitis）为一种遗传有密切关系的皮肤疾病，是指因遗传导致皮肤异常因而病变，会反复发作且搔痒难当即异常敏感，好发于婴幼儿时期。异位性皮肤炎痒也是异位性皮肤炎最主要的特征，同时易伴随其它过敏性体质，目前发病机制仍然未解。初次发作多于婴幼儿时期，总病患大约占总婴幼儿3%~5%，约30%的病患于1岁~5岁时发病，约有20%气喘病童会同时有此病症，更约有50%的异位性皮肤炎患者合并带有气喘、过敏性鼻炎的问题，此类病患通称异位性体质。