四种常见的非感染性肝病在北京302医院住院的患者2002年至2013

StephenW

Alcohol. 2016 Jul 18. pii: S0741-8329(15)30136-1. doi: 10.1016/j.alcohol.2016.07.001. [Epub ahead of print]
Changes of four common non-infectious liver diseases for the hospitalized patients in Beijing 302 hospital from 2002 to 2013.Chang B1, Li B1, Huang A1, Sun Y1, Teng G1, Wang X2, Liangpunsakul S3, Li J4, Zou Z5.
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AbstractThe implementation of a hepatitis B vaccination program in China has led to a significant decline in the prevalence and incidence of liver diseases secondary to hepatitis B virus over the past two decades. With recent changes in the economy and increases in average incomes in China during the same period, there has been a rapid rise in per capita alcohol consumption and an epidemic of obesity. We hypothesized that the burden of liver diseases in China has shifted from infectious to non-infectious etiologies. We retrospectively analyzed the data of 20,378 patients who were hospitalized in Beijing 302 hospital between 2002 and 2013. We found that the total admission rate secondary to alcoholic liver disease (ALD), non-alcoholic liver disease (NAFLD), autoimmune liver disease (AILD), and drug-induced liver injury (DILI) was 10.7%. ALD was the leading cause of inpatient hospitalization (3.9% of total admissions). The rate of inpatient admission for ALD, AILD, and DILI increased by 170%, 111%, and 107%, respectively during the study period. Chinese herbal medicine was the primary cause of DILI in our subjects. The burden of non-infectious liver diseases has increased over the last decade among hospitalized patients in a large tertiary hospital in China. The increase in the rate of admission for ALD and DILI from Chinese herbal medicine suggests that strategies to reduce harmful use of alcohol and increase awareness and education on the use of herbal medicine are needed.
Copyright © 2016 Elsevier Inc. All rights reserved.


KEYWORDS: Alcoholic liver disease; Autoimmune liver disease; Drug-induced liver injury; Non-alcoholic fatty liver disease; Non-infectious liver disease

PMID:27519542DOI:10.1016/j.alcohol.2016.07.001

StephenW

醇。 2016年18月PII：S0741-8329（15）30136-1。 DOI：10.1016 / j.alcohol.2016.07.001。 [打印EPUB提前]
四种常见的非感染性肝病在北京302医院住院的患者2002年至2013年的变化。
张B1，B1李，黄A1，孙Y1，滕G1，王X2，Liangpunsakul S3，李J4，邹Z5。
作者信息
抽象

在中国乙肝疫苗接种计划的实施导致了患病率显著下降，发病率在过去的二十年肝病继发乙肝病毒。随着经济和最近的变化在同一时期的平均收入在中国的增加，出现了人均酒精消费量迅速上升，肥胖的流行。我们假设，肝脏疾病在中国的负担已经从传染病转移到非感染性病因。我们回顾性分析谁被送进医院北京302 2002年和2013年之间的医院我们发现20378例患者的数据，总录取率继发于酒精性肝病（ALD），非酒精性肝病（NAFLD），自身免疫性肝病（AILD ）和药物性肝损伤（DILI）为10.7％。 ALD是住院治疗（共招生3.9％）的主要原因。住院手续的ALD，AILD和DILI率在研究期间分别增加了170％，111％和107％。中国的草药是DILI在我们的研究对象的主要原因。非感染性肝病的负担住院患者中增加了在过去十年在中国的大型三级医院。从中国中草药入场ALD和DILI率的上升表明，战略，以减少有害使用酒精和增加需要使用中草药的认识和教育。

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关键词：

酒精性肝病;自身免疫性肝病;药物性肝损伤;非酒精性脂肪肝病;非感染性肝病

结论：
    27519542
DOI：
    10.1016 / j.alcohol.2016.07.001