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Replicor宣布授予对HBV / HDV的治疗方法美国专利相结合的HBsAg减 [复制链接]

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发表于 2015-11-10 13:38 |只看该作者 |倒序浏览 |打印

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Replicor announces grant of US patents on HBV / HDV treatment methods combining HBsAg reduction and immunotherapy

[p=25, null, left]NEW YORK, November 9, 2015 – Replicor Inc., a privately held biopharmaceutical company targeting a cure for patients with chronic hepatitis B virus (HBV) and chronic HBV and hepatitis delta virus (HDV) co-infection, announces allowance by the United States Patent and Trademark Office of its patent applications describing methods for the treatment of chronic HBV and HDV that combine treatment with agents that can reduce serum HBsAg and immunotherapeutic agents.

[p=25, null, left]These allowed patents, protect the use of methods to treat patients with HBV infection or HBV / HDV co-infection that include combining different technologies that can be used to lower surface antigen in the blood of patients with different immunotherapeutic agents.  Protected agents to lower serum HBsAg include nucleic acid polymers or any siRNA targeting the cleavage of HBV mRNA at any location within the region encoding HBsAg.  Protected immunotherapeutic agents include pegylated interferons and a variety of other immunotherapeutic agents approved for or in development for the treatment of HBV infection.

[p=25, null, left]“With the evolving awareness that combining HBsAg elimination with immunotherapy will be key to achieving high rates of functional cure in patients with chronic HBV infection, these patents provide Replicor with a dominant intellectual property position in the field,” said Dr. Michel Bazinet, CEO.

[p=25, null, left]About Replicor

[p=25, null, left]Replicor is a privately held biopharmaceutical company with the most advanced animal and human clinical data in the development of the cure for HBV and HDV. The company is dedicated to accelerating the development of an effective treatment for patients with HBV and HBV/HDV infection. For further information about Replicor please visit our website at www.replicor.com or follow us on Twitter @replicorinc.

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发表于 2015-11-10 13:38 |只看该作者
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Replicor宣布授予对HBV / HDV的治疗方法美国专利相结合的HBsAg减少和免疫治疗

纽约,2015年11月9日 - Replicor公司,靶向治疗慢性乙型肝炎病毒(HBV)和慢性乙型肝炎和丁型肝炎病毒(HDV)合并感染一家私人持有的生物制药公司,由美国公布津贴其专利申请描述​​用于慢性HBV和HDV的相结合的治疗剂,可降低血清HBsAg和免疫治疗剂的治疗方法的专利和商标局。

这些专利允许,保护使用方法治疗患者以HBV感染或HBV / HDV共同感染,包括组合,可以用来对下表面抗原在患者的不同免疫治疗剂的血液不同的技术。降低保护剂血清HBsAg包括核酸聚合物或针对乙肝病毒mRNA的裂解的区域编码的HBsAg内的任何位置,任何的siRNA。保护的免疫治疗剂包括聚乙二醇化的干扰素和其它多种免疫治疗剂批准或处于发展为HBV感染的治疗。

“随着不断变化的认识到,结合乙肝表面抗原消除免疫疗法将是关键,在慢性HBV感染者达到功能性治愈率高,这些专利提供Replicor在该领域的主导的知识产权地位,”米歇尔Bazinet的博士,首席执行官。

关于Replicor

Replicor是一家私营生物制药公司,在治疗HBV和HDV的发展最先进的动物和人体的临床数据。该公司致力于加快有效治疗的发展,患者的HBV和HBV / HDV感染。有关Replicor更多信息,请访问我们的网站www.replicor.com或关注我们的微博@replicorinc。
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