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肝胆相照论坛 论坛 学术讨论& HBV English Michael J. Sofia Named Economist's 2015 Innovation A ...
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Michael J. Sofia Named Economist's 2015 Innovation Award [复制链接]

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发表于 2015-10-19 09:50 |只看该作者 |倒序浏览 |打印
VANCOUVER, British Columbia and DOYLESTOWN, Pa., Oct. 15, 2015 (GLOBE NEWSWIRE) -- Arbutus Biopharma Corporation (Nasdaq:ABUS), an industry-leading therapeutic solutions company focused on developing a cure for chronic hepatitis B virus infection (HBV), today announced that Dr. Michael J. Sofia, Arbutus' Chief Scientific Officer has won the Economist's 2015 Innovation Award in the Bioscience category, for developing a rapid cure for hepatitis C virus infection (HCV).

HCV affects 150 million people worldwide with an annual mortality rate of half a million patients globally. While traditional treatments only cure about 50 percent of cases after as much as a year of therapy, Sovaldi (originally named Sofosbuvir after its inventor, Dr. Sofia) can cure 90 percent of patients in only 12 to 24 weeks.

"I am honored to have been selected to receive the 2015 Innovation Award in Biosciences. It is a recognition of the real hope that sofosbuvir now gives to those suffering from the debilitating effects of HCV and the reality that they can now look forward to a normal life free from this disease," said Dr. Michael J. Sofia, Arbutus' Chief Scientific Officer. "At Arbutus our focus is on developing a curative therapy for patients with HBV, a disease with an even higher prevalence and greater unmet medical need. We are leveraging lessons learned from HCV to inform our strategy for building the leading HBV pipeline and developing proprietary drug combinations. "

About Arbutus

Arbutus Biopharma Corporation is a biopharmaceutical company dedicated to discovering, developing and commercializing a cure for patients suffering from chronic hepatitis B infection (HBV). Our strategy is to target the three pillars necessary to develop a curative regimen for HBV: suppressing HBV replication within liver cells, stimulating and reactivating the body's immune system so that it can mount an effective defense against the virus and, eliminating the reservoir of viral genomic material known as covalently closed circular DNA, or cccDNA that is the source of HBV persistence. Our portfolio of assets includes a broad pipeline of drug candidates for use in combination to develop a cure for HBV. To support continuous discovery of potential novel drug candidates and technologies, Arbutus has a research collaboration agreement with the Baruch S. Blumberg Institute that provides exclusive rights to in-license any intellectual property generated through the relationship. The Baruch S. Blumberg Institute was established in 2003 by the Hepatitis B Foundation.

Arbutus is headquartered in Vancouver, BC, Canada with offices in Doylestown, PA, USA. For more information, visit www.arbutusbio.com.

About the Economist's Innovation Awards

In this annual awards program, The Economist showcases creative people who dream up new ideas and turn them into reality. The newspaper invites its readers to nominate outstanding innovators in seven categories: Bioscience, Computing and Telecommunications, Consumer Products, Energy and the Environment, Process and Service Innovation, Social and Economic Innovation, and a special "no boundaries" category for innovations that span industries and sectors. In addition, the judges select the winner of the Corporate award for innovation.

Over the past 14 years, The Economist's Innovation Awards program has recognized the work of the world's leading entrepreneurs, thinkers, creators, scientists and innovators, including Steve Jobs, Mark Zuckerberg, Hernando de Soto and Elon Musk.

CONTACT: Investors

         Adam Cutler

         Senior Vice President, Corporate Affairs

         Phone: 604.419.3200

         Email: [email protected]

         

         Helia Baradarani

         Manager, Investor Relations

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发表于 2015-10-19 09:51 |只看该作者
温哥华,不列颠哥伦比亚省和DOYLESTOWN,宾夕法尼亚州,2015年10月15号(中国商业电讯) - 杨梅生物制药公司(纳斯达克股票代码:安博),业界领先的治疗解决方案公司,致力于开发一种治疗慢性乙型肝炎病毒感染(HBV )今天宣布,迈克尔博士J.索菲亚,杨梅“首席科学官,赢得了经济学家的2015年创新奖在生物科学类,用于开发快速治愈丙型肝炎病毒感染(HCV)。

HCV影响到1.5亿人的全球年均死亡率全球五十万的患者。尽管经过多达一年的治疗传统疗法只治病的病例约50%,Sovaldi(最初它的发明者,索菲亚博士的名字命名索非布韦)可以治愈90%的患者中只有12〜24周。

“我很荣幸能够被选中获得2015年创新奖在生物科学,这是一个认识的真正的希望,现在索非布韦给予那些来自HCV的破坏性影响与现实的痛苦,他们现在可以期待一个正常的生活不受这种疾病,博士说:“迈克尔·索菲亚,杨梅”首席科学官说。 “在杨梅我们的重点是开发一种根治性治疗的患者的乙肝病毒,这种疾病与更高的发病率和更大的未满足的医疗需求。我们正在利用教训HCV教训告诉我们的战略建立在领先的乙肝管道和开发专利药组合。“

关于杨梅

杨梅生物制药公司是一家生物制药公司,致力于发现,开发和商业化的治疗方法患慢性乙肝病毒感染(HBV)的痛苦。我们的策略是瞄准必要制定一个治疗方案治疗乙肝的三大支柱:抑制HBV复制的肝细胞中,刺激和重新激活人体的免疫系统,使其可以安装反病毒有效的防御和,消除了病毒基因组的水库材料被称为共价闭合环状DNA,或cccDNA的是乙肝病毒的持久性的来源。我们的资产组合包括候选药物的广泛的管道用于联合开发一种治疗乙肝。为了支持潜在的新候选药物和技术的不断发现,杨梅与巴鲁克S. Blumberg的研究所提供独家经营权的许可通过关系产生的任何知识产权方面的研究合作协议。巴鲁克S. Blumberg的研究所成立于2003年由乙型肝炎基金会。

杨梅总部设在温哥华,加拿大的Doylestown,宾夕法尼亚州,美国均设有办事处。欲了解更多信息,请访问www.arbutusbio.com

关于经济学的创新奖

在这一年度奖项,经济学家展示创意的人谁的梦想了新的思路,并把它们变成现实。本报邀请读者提名的杰出创新者在七类:生物科学,计算机和电信,消费品,能源和环境,流程和服务创新,社会和经济的创新,和一个特殊的“无界限”一类的跨产业创新和部门。此外,法官选择企业创新奖的得主。

在过去的14年中,经济学家的创新奖项目已经认识到世界领先的企业家,思想家,创造者,科学家和创新者,其中包括史蒂夫·乔布斯,扎克伯格,赫尔南多·德·索托和伊隆·马斯克的工作。

联系方式:投资者

         亚当·卡特勒

         高级副总裁,公司事务

         电话:604.419.3200

         电子邮件:[email protected]

         

         贺莉亚Baradarani

         投资者关系经理

         电话:604.419.3200

         电子邮件:[email protected]

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发表于 2015-10-19 10:26 |只看该作者
本帖最后由 newchinabok 于 2015-10-19 10:28 编辑

我力挺杨梅生物制药公司,但有的人说别人是美国大忽悠,真高见呀,认为别人是一群草包开的公司,自己最高明,真奇葩

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发表于 2015-10-19 15:51 |只看该作者
能治丙肝是好事

乙肝,希望成功吧~

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发表于 2015-10-20 10:58 |只看该作者
本帖最后由 newchinabok 于 2015-10-20 11:51 编辑

abus治乙肝思路很清晰,即研究rnai药物,也研究各靶点药,冲着联合用药而去。从来不会把某一种药放到绝对位置看待

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发表于 2015-10-20 12:03 |只看该作者
Our HBV product development pipeline is focused on discovering, acquiring or in-licensing, and developing drug candidates that attack multiple targets of the HBV lifecycle, including the aggressive suppression of HBV replication and the formation inhibition and elimination of cccDNA. These drug candidates may also boost the host immune response to chronic HBV infection.

Although the ultimate curative regimens for HBV are currently unknown, we have assembled an industry-leading portfolio of drug development programs targeting hepatitis B, which we will evaluate to determine the best potential combination approaches for patients.

By building a broad platform of direct antiviral and immune stimulation assets, we aim to optimize HBV combination curative strategies, with the ability to adapt our program focus quickly as the field continues to advance. Our combination approach can simultaneously inhibit viral replication, stimulate the host immune response to HBV and eliminate the reservoir of existing cccDNA.

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发表于 2015-10-20 12:05 |只看该作者
本帖最后由 newchinabok 于 2015-10-20 12:17 编辑

我们专注于发现,乙肝病毒产品开发管道收购或许可证,和开发药物候选人攻击乙肝病毒生命周期的多个目标,包括积极的抑制乙肝病毒复制和cccDNA的形成抑制和消除。这些候选药物也可能提高慢性乙型肝炎病毒感染宿主的免疫反应。
虽然乙肝病毒的最终治疗方案目前还不清楚,但是我们已经组建了一个行业领先的投资组合针对乙肝的药物开发项目,我们将评估,以确定最好的方法对病人潜在的组合
通过构建一个广阔的平台直接抗病毒和免疫刺激资产,我们的目标是优化治疗乙肝病毒组合策略,能够适应我们的项目重点领域不断进步很快。我们组合的方法可以同时抑制病毒复制,刺激宿主免疫反应乙肝病毒和消除现有cccDNA的水库。
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发表于 2015-10-20 12:07 |只看该作者
本帖最后由 newchinabok 于 2015-10-20 12:10 编辑

第一,不知道最终治愈hbv组合药物方案,第二,要优化方案

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发表于 2015-10-20 12:09 |只看该作者
本帖最后由 newchinabok 于 2015-10-20 12:22 编辑

没人说过一个药搞定hbv  ,arc520也没说过。认为一种药治愈乙肝,是战友自己瞎想的,不成功可别骂药企

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发表于 2015-10-20 20:48 |只看该作者
杨梅在合并oncore就成为了HBV攻战队中最有利的一支部队,希望他们能早日成功。
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