血清阳性率之间的育龄妇女在绵阳，中国乙肝表面抗原和乙

StephenW

J Infect Dev Ctries. 2015 Jul 30;9(7):770-779. doi: 10.3855/jidc.6938.
Seroprevalence of hepatitis B surface antigen and hepatitis B e antigen among childbearing-age women in Mianyang, China.Wang M1, Li H, Ji Y, Ma Y, Wang L, Ren T, Hou F, Yuan P.
Author information

• 1West China School of Public Health, Sichuan University, Chengdu, Sichuan, China. [email protected].
  

AbstractINTRODUCTION: Few studies have focused on hepatitis B virus (HBV) infection among childbearing-age women. This study explored hepatitis B surface antigen (HBsAg) seroprevalence and hepatitis B e antigen (HBeAg) seroprevalence and their associated factors among childbearing-age women.
METHODOLOGY: A cross-sectional, population-based study was conducted between June 2013 and October 2013 in Mianyang; women 15-49 years of age were enrolled using a multistage cluster sampling design. Participants completed questionnaires about demographic characteristics and potential factors associated with HBV infection, and provided blood samples for screening HBsAg and HBeAg. The analysis methods included descriptive statistics, Chi-square test, and multivariate logistic regression.
RESULTS: Among 62,007 childbearing-age women, 5.66% were HBsAg positive. The HBsAg seroprevalence rates were 7.28% in women 40-44 years of age, 7.0% in Fucheng women, 5.70% in Han women, 6.59% in married women, and 6.60% in agriculture workers. Multivariate models identified having HBsAg-positive family members, and having no self-reported immunization history to be positively associated with HBsAg positivity; being a healthcare worker was negatively associated with HBsAg positivity. Among 3,499 HBsAg-positive childbearing-age women, 9.97% were HBeAg positive. The HBeAg seroprevalence rates were 46.54% in women 15-19 years of age, 10.82% in Fucheng women, 38.51% in single women, and 42.86% in students. Multivariate models identified living in Fucheng and younger age to be positively associated with HBeAg positivity.
CONCLUSIONS: These findings could provide scientific evidence for the Chinese government to plan efficient health care services and prevention initiatives, and to allocate health resources reasonably for this population.

StephenW

Ĵ传染开发Ctries。 2015年7月30日; 9（7）：770-779。 DOI：10.3855 / jidc.6938。
血清阳性率之间的育龄妇女在绵阳，中国乙肝表面抗原和乙肝e抗原。
王M1，李H，姬Y，马Y，王琳，任T，侯男，袁P.
作者信息

    1West中国公共卫生学院，四川大学，成都，四川，中国的。 [email protected]。

抽象
简介：

一些研究都集中在乙型肝炎病毒（HBV）感染者生育年龄的妇女。本研究探讨乙肝表面抗原（HBsAg）血清阳性率和乙肝e抗原（HBeAg）血清阳性率和中育龄妇女的相关因素。
方法：

横断面，基于人口的研究是2013年6月和2013年10月在绵阳之间进行;采用多阶段整群抽样设计的女性15-49岁的患者。参与者完成有关与乙肝病毒感染相关的人口特征和潜在因素问卷调查，并提供了血液样本进行筛查HBsAg和HBeAg。该分析方法包括描述统计，卡方检验和多因素Logistic回归。
结果：

在62007育龄妇女，5.66％为HBsAg阳性。乙肝表面抗原血清阳性率在女性40-44岁，涪城女性7.0％，在汉族妇女5.70％，在已婚妇女6.59％，而农业劳动者6.60％，7.28％。确定具有HBsAg阳性家庭成员，且没有自报免疫史可积极与乙肝表面抗原阳性关联的多变量模型;被医护人员带负电，乙肝表面抗原阳性关联。在3499 HBsAg阳性育龄妇女，9.97％为HBeAg阳性。 HBeAg的血清阳性率分别为女性15-19岁，涪城女性10.82％，在单身女性38.51％，而在学生42.86％，46.54％。确定居住在阜城和低龄多变量模型进行积极的HBeAg阳性关联。
结论：

这些发现可以提供科学依据，为中国政府计划高效的医疗服务和预防措施，并合理配置卫生资源对这个群体