乙肝病毒的患者有较高的发病率纤维肌痛

StephenW

Hepatitis B Virus Patients Have a Higher Fibromyalgia Incidence
Patricia Silva, PhD

A new study entitled “Fibromyalgia incidence among patients with hepatitis B infection” recently revealed that patients infected with the hepatitis B virus (HBV) have a higher incidence of fibromyalgia. The study was published in the International Journal of Rheumatic Diseases and was conducted by researchers at Dicle University and the Yüzüncüyıl University in Turkey.

HBV infection is a potentially life-threatening condition that affects the liver and can cause both acute and chronic disease, increasing the patient’s risk of death from cirrhosis and liver cancer. It has been previously reported that patients infected with HBV have a high incidence of fibromyalgia, a disorder characterized by widespread chronic musculoskeletal pain, incapacitating fatigue, stiffness and numbness in certain parts of the body, painful response to pressure, headaches, unrefreshing sleep (poor sleep quality), anxiety or depression and mood alterations. Fibromyalgia can affect people’s ability to conduct simple daily tasks, compromising their quality of life.

Researchers have now evaluated the incidence of fibromyalgia among HBV patients and the associated clinical symptoms. In total, 118 HBV patients (mean age of 36 years) were assessed. Patients were divided into three groups: HBV carriers (40 patients), chronic active HBV patients (40 patients) and patients who had been treated with antiretroviral therapy for at least 3 months (38 patients). As a control group, 60 sex and age matched healthy individuals were also analyzed.

The team found that the serum levels of the liver enzymes aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were significantly higher in HBV patients than in the control group, indicating liver damage. HBV patients also had a significantly higher fibromyalgia incidence, arthralgia (joint pain), widespread pain, sleep disturbance, fatigue, morning stiffness and anxiety in comparison to the control group. No differences were found in AST and ALT levels, fibromyalgia incidence, arthralgia, widespread pain, sleep disturbance and anxiety between the three groups of patients. The only exception was the mean body mass index that was found to be significantly higher in the HBV carrier group.

The research team concluded that HBV patients have indeed a higher fibromyalgia incidence in comparison to healthy controls, and propose HBV as a potential independent predictor of the disorder. The team found no differences in fibromyalgia incidence among the three HBV groups analyzed.

StephenW

乙肝病毒的患者有较高的发病率纤维肌痛
帕特里夏·席尔瓦博士

题为“在乙肝患者感染发病纤维肌痛”一项新的研究最近发现，患者感染了乙型肝炎病毒（HBV）有纤维肌痛的发生率较高。这项研究结果发表在风湿性疾病的国际杂志，是由研究人员在Dicle大学和Yüzüncüyıl大学在土耳其进行。

HBV感染是一种潜在的威胁生命的情况，影响肝和可引起急性和慢性疾病，肝硬化和肝癌增加死亡的患者的风险。先前已经报道​​，患者感染HBV具有高发病率纤维肌痛，特征的病症广泛慢性肌肉骨骼疼痛，不适于疲劳，刚度和麻木在身体的某些部位，对压力疼痛反应，头痛，unrefreshing睡眠（差睡眠质量），焦虑或抑郁和情绪变化。纤维肌痛可以影响人的进行简单的日常任务的能力，影响他们的生活质量。

现在，研究人员评估纤维肌痛之间乙肝患者和相关的临床症状的发生率。总共118 HBV患者（平均36岁）进行了评估。将患者分为三组：乙肝病毒携带者（40例），谁曾接受抗逆转录病毒治疗至少3个月（38例），慢性活动性HBV患者（40例）和患者。作为对照组，60性别和年龄匹配的健康个体进行了分析。

研究小组发现，肝脏酶谷草转氨酶（AST）和丙氨酸氨基转移酶（ALT）的血清水平显著高于乙肝患者比对照组，提示肝损害。 HBV的患者也有一个显著更高纤维肌痛发生率，关节痛（关节疼痛），广泛疼痛，睡眠障碍，疲劳，晨僵和焦虑相比于对照组。没有差异，在AST和ALT水平，三组病人之间纤维肌痛发生率，关节痛，广泛疼痛，睡眠障碍和焦虑。唯一的例外是，被认为是显著更高的HBV携带者组中的平均体重指数。

该研究小组的结论是，乙肝患者有的确是一个较高的发病率纤维肌痛相比健康对照，并提出作为乙肝这种疾病的一个潜在的独立预测因子。研究小组发现中分析三组HBV纤维肌痛的发病率无显着差异。

咬牙硬挺

感谢分享

cangjingsora

回复 StephenW 的帖子

很有道理， 我就是经常肌肉酸痛， 十几年了。

吃替诺后感觉这个症状消失了。

四十己过

确实  我这两三年很明显，早晨起来肌无力，前一天不运动，第二天就没力量。开车超一个半小时，也会小腿麻木。唉……

南湖淋雨

这个症状我早就有了，小三阳，抗原57IU，KNA1300IU