微波消融的大病灶肝癌治疗的价值

StephenW

Value of Microwave Ablation in Treatment of large lesions of Hepatocellular Carcinoma

    Eman Medhat1, Ashraf Abdel Aziz1, Mohammed Nabeel1, Tamer Elbaz1, Zeinab Zakaria1,*, Hend Shousha1, Ayman Amer1, Waleed Fouad Fathalah1, Rabab Maher2 andShereif Musa1

DOI: 10.1111/1751-2980.12259


Cover image for Vol. 16 Issue 4
Journal of Digestive Diseases

Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)


   
Abstract
Background and study aims

Thermal ablative therapies continue to acquire favor to be safe and effective for the treatment of patients with non resectable hepatocellular carcinoma. Percutaneous microwave ablative therapy which is a relatively new technique has the advantage in providing faster ablation of larger tumors. This study aimed to evaluate microwave ablation in treatment of large HCCs (5-7cm) and to assess its effect on local tumor progression, prognostic outcome and patient's survival.
Methods

Twenty six patients with HCC lesions (5-7cm) were managed in our multidisciplinary clinic of Kasr Al Ainy University hospital using microwave ablation. It was performed with the patient under conscious sedation and analgesia, ultrasonography guided using HS AMICA microwave machine, operating at frequency of 2450 MHz and a power up to 100 W. Multiple needle insertions in one or two sessions according to the size of the lesion. Patients were assessed for efficacy and safety. Complete ablation rate, local tumor progression and overall survival analysis were evaluated.
Results

Complete ablation was achieved in (19/ 26; 73.1%) of the lesions. Local tumor progression was recorded in 5 treated lesions (19.2%). Distant tumor progression within the liver was recorded in 6 patients (23.1%), with a mean survival of 21.5 months. No major complications or deaths related to the procedure.
Conclusion

Microwave ablation by percutaneous approach is safe and effective in the treatment of large HCC tumor. The survival and local tumor control were acceptable.

StephenW

微波消融的大病灶肝癌治疗的价值

    埃曼Medhat1阿什拉夫·阿卜杜勒·Aziz1，穆罕默德Nabeel1，驯Elbaz1，泽纳布Zakaria1，*，亨德Shousha1，艾曼Amer1，瓦利德福阿德Fathalah1，Rabab Maher2 andShereif Musa1

DOI：10.1111 / 1751-2980.12259


封面图片卷。 16第4期
中华消化病

接受第（接受，未编辑的文章，并在网上公布可引用的最终编辑和记录的排版本将出现在未来。）


   
抽象
研究的背景和目的

热消融疗法继续获取青睐是安全和有效地用于治疗非可切除肝细胞癌的治疗。经皮微波消融治疗是一种相对较新的技术具有以下优点：在提供的较大的肿瘤更快消融。本研究旨在评估微波消融治疗肝癌的大（5-7cm），并评估其对局部肿瘤进展，预后效果和患者的生存影响。
方法

二十六例肝癌病灶（5-7cm）在我们的多学科的使用微波消融Kasr铝Ainy大学医院门诊进行管理。它用下清醒镇静和止痛，超声使用HS AMICA微波机，在2450 MHz和一个功率高达100W。多个针插入在一个或两个会议根据病变的大小频率下操作指导患者进行的。评估患者的有效性和安全性。完全消融率，局部肿瘤进展和总生存分析进行了评价。
结果

病变;在完全消融达到（73.1％19/26）。局部肿瘤进展录得5治疗病变（19.2％）。肝脏内的遥远的肿瘤进展录得6例（23.1％），21.5个月，平均生存期。无严重并发症或死亡相关的程序。
结论

微波消融经皮的方法是安全，有效的大肝癌肿瘤的治疗。生存和肿瘤局部控制是可以接受的。