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回复 hao2014 的帖子
Recruiting Study of Azacitidine With or Without Birinapant in Subjects With MDS or CMMoL
Conditions: Myelodysplastic Syndrome (MDS); Chronic Myelomonocytic Leukemia (CMML)
Interventions: Drug: birinapant; Drug: Azacitidine; Drug: Placebo
2 Active, not recruiting Phase I Safety and Tolerability Study of Birinapant in Chronic Hepatitis B
Condition: Hepatitis B
Interventions: Drug: Antiviral Therapy (tenofovir or entecavir); Drug: Birinapant; Drug: Placebo (for birinapant)
3 Active, not recruiting Birinapant With 5-azacitidine in MDS Subjects Who Are Naïve, Have Relapsed or Are Refractory to 5-azacitidine Therapy
Condition: Myelodysplastic Syndrome
Interventions: Drug: TL32711; Drug: 5-Azacitidine
4 Recruiting Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian Cancer
Conditions: Relapsed Epithelial Ovarian Cancer; Relapsed Primary Peritoneal Cancer; Relapsed Fallopian Tube Cancer
Interventions: Drug: Birinapant; Drug: Conatumumab
5 Completed Dose Escalation, Combination Chemotherapy Safety Study of TL32711, in Subjects With Advanced or Metastatic Solid Tumors
Condition: Cancer
Intervention: Drug: TL32711
6 Completed
Has Results Birinapant for Advanced Ovarian, Fallopian Tube, and Peritoneal Cancer
Conditions: Epithelial Ovarian Cancer; Peritoneal Neoplasms; Fallopian Tube Neoplasms
Intervention: Drug: Birinapant (TL32711)
7 Terminated Gemcitabine Hydrochloride and Smac Mimetic TL32711 in Treating Patients With Advanced Solid Tumors
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: Smac mimetic TL32711; Drug: gemcitabine hydrochloride; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: biopsy
8 Withdrawn 18F-CP18 Imaging Studies for Cancer Treatment With Birinapant
Conditions: Ovarian Neoplasms; Ovarian Cancer; Fallopian Tube Neoplasms; Fallopian Tube Cancer
Interventions: Drug: [18F]-CP18; Procedure: PET/ CT
9 Completed Dose Escalation Safety Study of TL32711 in Adults With Refractory Solid Tumors or Lymphoma
Condition: Cancer
Intervention: Drug: TL32711
10 Completed A Phase I-II Open Label Non-Randomized Study Using TL32711 for Patients With Acute Myelogenous Leukemia, Myelodysplastic Syndrome and Acute Lymphoblastic Leukemia
Condition: Acute Myelogenous Leukemia
Intervention: Drug: TL32711
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