瞬时弹性的慢性病毒性肝炎接受抗病毒治疗的临床应用

StephenW

Clinical application of transient elastography in patients with chronic viral hepatitis receiving antiviral treatment

    Jun Hyung Kim1,†,
    Mi Na Kim1,2,3,†,
    Kwang-Hyub Han1,2,3 and
    Seung Up Kim1,2,3,*

Article first published online: 19 JUL 2014

DOI: 10.1111/liv.12628

© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

Issue
Liver International

Volume 35, Issue 4, pages 1103–1115, April 2015
Article has an altmetric score of 1


Author Information
    1    Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
    2    Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea
    3    Liver Cirrhosis Clinical Research Center, Seoul, Korea

    †    Both authors contributed equally to this work.

* Correspondence
Seung Up Kim, MD
Department of Internal Medicine, Yonsei University College of Medicine
50 Yonsei-ro, Seodaemun–gu, Seoul 120–752, South Korea
Tel: 82-2-2228-1982
Fax: 82-2-393-6884
e-mail: [email protected]


Abstract

Accurate evaluation of the degree of liver fibrosis in patients with chronic liver diseases (CLD) is crucial, as liver fibrosis is important in determining the prognosis of liver diseases. Currently, liver biopsy (LB) is considered the gold standard for staging liver fibrosis or cirrhosis. However, utilization of LB in clinical practice is often limited because of its invasive nature, sampling error and interobserver variability. Recently, transient elastography (TE) was introduced as a noninvasive, highly reproducible technique for assessing the degree of liver fibrosis. After extensive studies, TE is now regarded as a reliable surrogate marker for grading the severity of liver fibrosis in patients with CLD. In the past few years, the role of TE in monitoring liver stiffness and determining prognosis in patients with chronic hepatitis B (CHB) or chronic hepatitis C (CHC) who are undergoing antiviral treatment has been investigated. In patients with CHB, liver stiffness values decrease with antiviral treatment. TE can also be used to predict the incidence of liver-related events during antiviral treatment. In patients with CHC, TE can be used to monitor potential regression of liver fibrosis after antiviral treatment and may predict the treatment outcome of CHC. In addition, TE is an adjunct tool for distinguishing inactive hepatitis B virus carriers from patients with chronic active hepatitis. This review article discusses the important findings from recent studies focusing on the clinical application of TE in patients with chronic viral hepatitis who are undergoing antiviral treatments.

StephenW

瞬时弹性的慢性病毒性肝炎接受抗病毒治疗的临床应用

    俊亨Kim1，†，
    宓嗯啊Kim1,2,3，†，
    刘广Hyub Han1,2,3和
    升向上Kim1,2,3，*

文章首次在网上公布：2014年7月19日

DOI：10.1111 / liv.12628

©2014年约翰·威利父子A / S。发布时间由John Wiley＆Sons出版有限公司

问题
肝国际

第35卷，第4期，一一零三年至1115年的网页，2015年4月
第二十有altmetric比分1


作者信息
    内科，医学延世大学，首尔，韩国1系
    消化内科2研究所，医学延世大学，汉城
    3肝硬化临床研究中心，汉城

    †两位作者同等贡献这项工作。

*通讯
升最多金，MD
内科，延世大学医学院
50延世-RO，西大门区，首尔120-752，韩国
电话：82-2-2228-1982
传真：82-2-393-6884
电子邮件：[email protected]


抽象

肝纤维化的慢性肝脏疾病的程度的准确的评价（CLD）是至关重要的，如肝纤维化是确定肝脏疾病的预后很重要的。目前，肝活检（LB）被认为是黄金标准分期肝纤维化或肝硬化。然而，在临床实践中的运用LB往往是有限的，因为它的侵入性，抽样误差和观察者之间的差异。最近，瞬时弹性成像（TE）是作为一种非侵入性的，高度可再现的技术用于评估肝纤维化的程度。经过广泛的研究，TE现在被认为是一个可靠的替代指标与CLD分级肝纤维化的严重程度的患者。在过去的几年中，TE在监测肝脏硬度和确定治疗慢性乙型肝炎（CHB），慢性丙型肝炎（CHC）谁正在接受抗病毒治疗预后的作用进行了研究。在慢性乙肝患者，肝脏硬度值降低抗病毒治疗。 TE也可以使用在抗病毒治疗，预测肝脏相关的事件的发生率。在CHC患者，TE能够被用于监控肝纤维化的抗病毒治疗后的潜在回归和可预测CHC的治疗​​结果。此外，TE是一个辅助工具，从慢性活动性肝炎区别不活跃乙肝病毒携带者。此综述文章从最近的研究集中于TE中治疗慢性病毒性肝炎谁正在接受抗病毒治疗的临床应用讨论了重要的发现。

682256

TE是否就是B超？瞬时弹性成像？

StephenW

回复 682256 的帖子

TE是瞬时弹性成像, Fibroscan.

682256

就是当下流行的飞波吧，谢了